We report here the case of a 32-year-old male with recent diagnosis of HIV that, 45 days after starting a single tablet regimen co-formulated with bictegravir, emtricitabine and tenofovir alafenamide (BIC/FTC/TAF), experienced severe epigastric pain radiating to the back, nausea, episodes of non-bloody non-bilious vomiting and anorexia. Laboratory examination showed a rise in lipase with no alterations in serum transaminases. Abdominal ultrasound revealed a non-homogeneous structure of the pancreatic parenchyma. A diagnosis of mild drug-related acute pancreatitis was made and BIC/FTC/TAF was immediately stopped. The association between the episode of acute pancreatitis and BIC/FTC/TAF was scored as probable according to the Naranjo causality scale.
Bictegravir/emtricitabine/tenofovir alafenamide-induced acute pancreatitis : a case report / A. Riva, D. Cattaneo, C. Filice, C. Gervasoni. - In: INTERNATIONAL JOURNAL OF STD & AIDS. - ISSN 0956-4624. - 31:10(2020), pp. 1008-1010. [10.1177/0956462420934981]
Bictegravir/emtricitabine/tenofovir alafenamide-induced acute pancreatitis : a case report
A. Riva;
2020
Abstract
We report here the case of a 32-year-old male with recent diagnosis of HIV that, 45 days after starting a single tablet regimen co-formulated with bictegravir, emtricitabine and tenofovir alafenamide (BIC/FTC/TAF), experienced severe epigastric pain radiating to the back, nausea, episodes of non-bloody non-bilious vomiting and anorexia. Laboratory examination showed a rise in lipase with no alterations in serum transaminases. Abdominal ultrasound revealed a non-homogeneous structure of the pancreatic parenchyma. A diagnosis of mild drug-related acute pancreatitis was made and BIC/FTC/TAF was immediately stopped. The association between the episode of acute pancreatitis and BIC/FTC/TAF was scored as probable according to the Naranjo causality scale.File | Dimensione | Formato | |
---|---|---|---|
0956462420934981.pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Dimensione
314.03 kB
Formato
Adobe PDF
|
314.03 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.