IRIS Institutional Research Information System - AIR Archivio Istituzionale della Ricerca
IRIS è il sistema di gestione integrata dei dati della ricerca (persone, progetti, pubblicazioni, attività) adottato dall'Università degli Studi di Milano.
AIR nasce in UNIMI nel 2006 con lo scopo di raccogliere, documentare e conservare le informazioni sulla produzione scientifica dell'Università degli Studi di Milano e costituisce di fatto l'Anagrafe della ricerca dell'Ateneo.
EnglishBackground: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus responsible for the coronavirus disease of 2019 (COVID-19) that emerged in December 2019 in Wuhan, China, and rapidly spread worldwide, with a daily increase in confirmed cases and infection-related deaths. The World Health Organization declared a pandemic on the 11th of March 2020. COVID-19 presents flu-like symptoms that become severe in high-risk medically compromised subjects. The aim of this study was to perform an updated overview of the treatments and adjuvant protocols for COVID-19. Methods: A systematic literature search of databases was performed (MEDLINE PubMed, Google Scholar, UpToDate, Embase, and Web of Science) using the keywords: “COVID-19”, “2019-nCoV”, “coronavirus” and “SARS-CoV-2” (date range: 1 January 2019 to 31st October 2020), focused on clinical features and treatments. Results: The main treatments retrieved were antivirals, antimalarials, convalescent plasma, immunomodulators, corticosteroids, anticoagulants, and mesenchymal stem cells. Most of the described treatments may provide benefits to COVID-19 subjects, but no one protocol has definitively proven its efficacy. Conclusions: While many efforts are being spent worldwide in research aimed at identifying early diagnostic methods and evidence-based effective treatments, mass vaccination is thought to be the best option against this disease in the near future.
The 15-months clinical experience of sars-cov-2: A literature review of therapies and adjuvants / A.D. Inchingolo, G. Dipalma, A.M. Inchingolo, G. Malcangi, L. Santacroce, M.T. D'oria, C.G. Isacco, I.R. Bordea, S. Candrea, A. Scarano, B. Morandi, M.D. Fabbro, M. Farronato, G.M. Tartaglia, M.G. Balzanelli, A. Ballini, L. Nucci, F. Lorusso, S. Taschieri, F. Inchingolo. - In: ANTIOXIDANTS. - ISSN 2076-3921. - 10:6(2021), pp. 881.1-881.43. [10.3390/antiox10060881]
| Titolo: | The 15-months clinical experience of sars-cov-2: A literature review of therapies and adjuvants | |
| Autori: | ||
| Parole Chiave: | SARS-CoV-2 (COVID-19); vaccines; anticoagulants; antioxidants; antivirals; antimalarials; immunotherapy; immunomodulators; corticosteroids; autologous stem cells | |
| Settore Scientifico Disciplinare: | Settore MED/50 - Scienze Tecniche Mediche Applicate Settore MED/28 - Malattie Odontostomatologiche | |
| Data di pubblicazione: | 2021 | |
| Rivista: | ||
| Tipologia: | Article (author) | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.3390/antiox10060881 | |
| Appare nelle tipologie: | 01 - Articolo su periodico |
File in questo prodotto:
| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| antioxidants 2021-10-00881-Inchingolo.pdf | Publisher's version/PDF | Open Access Visualizza/Apri |
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