OBJECTIVE: The aim of this study was to investigate the association between extracoronary artery diameter (brachial and carotid arteries) and obesity. METHODS: This was a cross-sectional study conducted among women referred to the Menopause Clinic of the University of Catanzaro. The study included 102 obese and 102 nonobese (controls) postmenopausal women. Medical histories were reviewed, and participants underwent clinical and biochemical evaluations to assess risk factors for cardiovascular disease. Common carotid artery and brachial artery diameters and atherosclerotic lesions were evaluated by ultrasonography. Associations between brachial artery and common carotid artery diameters with age, body mass index, waist circumference, and cardiovascular risk factors were analyzed by stepwise multivariate analysis. RESULTS: Brachial and common carotid artery diameters were significantly greater in obese women than in nonobese women. After adjustment for confounding variables, brachial artery diameter but not common carotid artery diameter correlated with obesity (β = 0.229, P = 0.002) and with waist circumference (β = 0.013, P < 0.001) independently of systolic blood pressure and other risk factors. CONCLUSIONS: Extracoronary artery diameter measurement, if confirmed by other studies, may be considered a useful tool to assess vascular remodeling in obese postmenopausal women.

Large extracoronary artery diameter in obese postmenopausal women / T. Montalcini, A. Fava, A. Castagna, G. Gorgone, C. Gazzaruso, A. Pujia. - In: MENOPAUSE. - ISSN 1072-3714. - 17:3(2010), pp. 611-614. [10.1097/gme.0b013e3181d2ce6d]

Large extracoronary artery diameter in obese postmenopausal women

C. Gazzaruso
Penultimo
;
2010

Abstract

OBJECTIVE: The aim of this study was to investigate the association between extracoronary artery diameter (brachial and carotid arteries) and obesity. METHODS: This was a cross-sectional study conducted among women referred to the Menopause Clinic of the University of Catanzaro. The study included 102 obese and 102 nonobese (controls) postmenopausal women. Medical histories were reviewed, and participants underwent clinical and biochemical evaluations to assess risk factors for cardiovascular disease. Common carotid artery and brachial artery diameters and atherosclerotic lesions were evaluated by ultrasonography. Associations between brachial artery and common carotid artery diameters with age, body mass index, waist circumference, and cardiovascular risk factors were analyzed by stepwise multivariate analysis. RESULTS: Brachial and common carotid artery diameters were significantly greater in obese women than in nonobese women. After adjustment for confounding variables, brachial artery diameter but not common carotid artery diameter correlated with obesity (β = 0.229, P = 0.002) and with waist circumference (β = 0.013, P < 0.001) independently of systolic blood pressure and other risk factors. CONCLUSIONS: Extracoronary artery diameter measurement, if confirmed by other studies, may be considered a useful tool to assess vascular remodeling in obese postmenopausal women.
Brachial artery diameter; Obesity; Postmenopausal women
Settore MED/13 - Endocrinologia
Settore MED/09 - Medicina Interna
Article (author)
File in questo prodotto:
File Dimensione Formato  
2010 Menopause.pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 84.68 kB
Formato Adobe PDF
84.68 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/859432
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 4
  • ???jsp.display-item.citation.isi??? 4
social impact