Bioinformatics tools are imperative for the in depth analysis of heterogeneous high-throughput data. Most of the software tools are developed by specific laboratories or groups or companies wherein they are designed to perform the required analysis for the group. However, such software tools may fail to capture “what the community needs in a tool”. Here, we describe a novel community-driven approach to build a comprehensive functional enrichment analysis tool. Using the existing FunRich tool as a template, we invited researchers to request additional features and/or changes. Remarkably, with the enthusiastic participation of the community, we were able to implement 90% of the requested features. FunRich enables plugin for extracellular vesicles wherein users can download and analyse data from Vesiclepedia database. By involving researchers early through community needs software development, we believe that comprehensive analysis tools can be developed in various scientific disciplines.

A novel community driven software for functional enrichment analysis of extracellular vesicles data / M. Pathan, S. Keerthikumar, D. Chisanga, R. Alessandro, C.-. Ang, P. Askenase, A.O. Batagov, A. Benito-Martin, G. Camussi, A. Clayton, F. Collino, D. di Vizio, J.M. Falcon-Perez, P. Fonseca, P. Fonseka, S. Fontana, Y.S. Gho, A. Hendrix, E. Nolte-'T Hoen, N. Iraci, K. Kastaniegaard, T. Kislinger, J. Kowal, I.V. Kurochkin, T. Leonardi, Y. Liang, A. Llorente, T.R. Lunavat, S. Maji, F. Monteleone, A. Overbye, T. Panaretakis, T. Patel, H. Peinado, S. Pluchino, S. Principe, G. Ronquist, F. Royo, S. Sahoo, C. Spinelli, A. Stensballe, C. Thery, M.J.C. van Herwijnen, M. Wauben, J.L. Welton, K. Zhao, S. Mathivanan. - In: JOURNAL OF EXTRACELLULAR VESICLES. - ISSN 2001-3078. - 6:1(2017), pp. 1321455.1-1321455.4. [10.1080/20013078.2017.1321455]

A novel community driven software for functional enrichment analysis of extracellular vesicles data

F. Collino;
2017

Abstract

Bioinformatics tools are imperative for the in depth analysis of heterogeneous high-throughput data. Most of the software tools are developed by specific laboratories or groups or companies wherein they are designed to perform the required analysis for the group. However, such software tools may fail to capture “what the community needs in a tool”. Here, we describe a novel community-driven approach to build a comprehensive functional enrichment analysis tool. Using the existing FunRich tool as a template, we invited researchers to request additional features and/or changes. Remarkably, with the enthusiastic participation of the community, we were able to implement 90% of the requested features. FunRich enables plugin for extracellular vesicles wherein users can download and analyse data from Vesiclepedia database. By involving researchers early through community needs software development, we believe that comprehensive analysis tools can be developed in various scientific disciplines.
Bioinformatics; Extracellular vesicles; FunRich
Settore MED/46 - Scienze Tecniche di Medicina di Laboratorio
Settore MED/04 - Patologia Generale
Settore BIO/13 - Biologia Applicata
2017
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/854356
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