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IRIS è il sistema di gestione integrata dei dati della ricerca (persone, progetti, pubblicazioni, attività) adottato dall'Università degli Studi di Milano.
AIR nasce in UNIMI nel 2006 con lo scopo di raccogliere, documentare e conservare le informazioni sulla produzione scientifica dell'Università degli Studi di Milano e costituisce di fatto l'Anagrafe della ricerca dell'Ateneo.
EnglishBackground: The question of whether solid malignancies (SMs) are associated with pyoderma gangrenosum (PG) remains to be conclusively answered.Objective: To evaluate the risk of SM among patients with PG and the odds of PG after a diagnosis of SM.Methods: A population-based retrospective cohort study was conducted to study the risk for SM in patients with PG (n = 302) as compared with age-, sex- and ethnicity-matched control subjects (n = 1799). A case-control design was used to estimate the odds of PG in those with a preexisting history of SM.Results: The prevalence of a preexisting SM was comparable in patients with PG and controls (7.5% vs. 8.8%, respectively; P = 0.490). The odds of having PG following a diagnosis of a SM was not statistically increased (OR, 0.85; 95% CI, 0.53-1.36). The incidence of SM was 6.8 (95% CI, 3.5-12.2) and 7.9 (95% CI, 6.1-10.1) per 1000 person-years among patients with PG and controls, respectively. Patients with PG were not more likely to develop SM as compared to controls (HR, 0.86; 95% CI, 0.44-1.69). Patients with a dual diagnosis of PG and SM were older and had more frequent comorbid conditions and increased mortality.Conclusions: SM is not associated with provoking PG, and patients with PG are not at an increased risk of developing SM. A thorough routine screening for SM in patients with new-onset PG is an unnecessary approach based on the study findings.
Is pyoderma gangrenosum associated with solid malignancies? Insights from a population‐based cohort study / K. Kridin, R. Laufer Britva, D. Tzur Bitan, G. Damiani, A. D Cohen. - In: AUSTRALASIAN JOURNAL OF DERMATOLOGY. - ISSN 0004-8380. - (2021). [Epub ahead of print]
| Titolo: | Is pyoderma gangrenosum associated with solid malignancies? Insights from a population‐based cohort study | |
| Autori: | DAMIANI, GIOVANNI (Penultimo) | |
| Parole Chiave: | Pyoderma gangrenosum; case-control study; cohort study; solid malignancies; | |
| Settore Scientifico Disciplinare: | Settore MED/35 - Malattie Cutanee e Veneree | |
| Data di pubblicazione: | 2021 | |
| Rivista: | ||
| Tipologia: | Article (author) | |
| Data ahead of print / Data di stampa: | giu-2021 | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1111/ajd.13631 | |
| Appare nelle tipologie: | 01 - Articolo su periodico |
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| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| ajd.13631.pdf | Publisher's version/PDF | Open Access Visualizza/Apri |
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