Intra-operative ultrasound has become a relevant imaging modality in neurosurgical procedures. While B-mode, with its intrinsic limitations, is still considered the primary ultrasound modality, intra-operative contrast-enhanced ultrasound (ioCEUS) has more recently emerged as a powerful tool in neurosurgery. Though still not used on a large scale, ioCEUS has proven its utility in defining tumor boundaries, identifying lesion vascular supply and mapping neurovascular architecture. Here we propose a step-by-step procedure for performing ioCEUS analysis of the brain, highlighting its neurosurgical applications. Moreover, we provide practical advice on the use of ultrasound contrast agents and review technical ultrasound parameters influencing ioCEUS imaging.

How to Perform Intra-Operative Contrast-Enhanced Ultrasound of the Brain-A WFUMB Position Paper / F. Prada, I.G. Vetrano, A.G. Gennari, G. Mauri, A. Martegani, L. Solbiati, L.M. Sconfienza, E. Quaia, K.N. Kearns, M.Y.S. Kalani, M.S. Park, F. DiMeco, C. Dietrich. - In: ULTRASOUND IN MEDICINE AND BIOLOGY. - ISSN 0301-5629. - (2021). [Epub ahead of print] [10.1016/j.ultrasmedbio.2021.04.016]

How to Perform Intra-Operative Contrast-Enhanced Ultrasound of the Brain-A WFUMB Position Paper

F. Prada;I.G. Vetrano;G. Mauri;L.M. Sconfienza;F. Dimeco;
2021

Abstract

Intra-operative ultrasound has become a relevant imaging modality in neurosurgical procedures. While B-mode, with its intrinsic limitations, is still considered the primary ultrasound modality, intra-operative contrast-enhanced ultrasound (ioCEUS) has more recently emerged as a powerful tool in neurosurgery. Though still not used on a large scale, ioCEUS has proven its utility in defining tumor boundaries, identifying lesion vascular supply and mapping neurovascular architecture. Here we propose a step-by-step procedure for performing ioCEUS analysis of the brain, highlighting its neurosurgical applications. Moreover, we provide practical advice on the use of ultrasound contrast agents and review technical ultrasound parameters influencing ioCEUS imaging.
Brain tumors; CEUS; Central nervous system; Contrast-enhanced ultrasound; Intraoperative ultrasounds; Neurosurgery; Neurovascular diseases
Settore MED/36 - Diagnostica per Immagini e Radioterapia
Settore MED/27 - Neurochirurgia
24-mag-2021
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/848587
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