T cell lymphoma (TCL) is a heterogenous group of lymphoid malignancies representing about 30–40% of all canine lymphomas and often harboring a very aggressive behavior. WHO classification identifies the majority of TCLs as peripheral TCL, but other subtypes with peculiar presentation and outcome have been recognized. This review aims to explore the use of flow cytometry for refining the diagnosis of canine TCL, putting a particular emphasis on the identification of some peculiar immunotypes, such as T zone lymphoma; on the investigation of putative prognostic markers; and on the evaluation of lymphoma stage and of the minimal residual disease.

Flow Cytometry in the Diagnosis of Canine T-Cell Lymphoma / S. Comazzi, F. Riondato. - In: FRONTIERS IN VETERINARY SCIENCE. - ISSN 2297-1769. - 8(2021), pp. 600963.1-600963.8.

Flow Cytometry in the Diagnosis of Canine T-Cell Lymphoma

S. Comazzi
;
2021

Abstract

T cell lymphoma (TCL) is a heterogenous group of lymphoid malignancies representing about 30–40% of all canine lymphomas and often harboring a very aggressive behavior. WHO classification identifies the majority of TCLs as peripheral TCL, but other subtypes with peculiar presentation and outcome have been recognized. This review aims to explore the use of flow cytometry for refining the diagnosis of canine TCL, putting a particular emphasis on the identification of some peculiar immunotypes, such as T zone lymphoma; on the investigation of putative prognostic markers; and on the evaluation of lymphoma stage and of the minimal residual disease.
diagnosis; dog; flow cytometry; lymphoma; prognosis; T-cell
Settore VET/03 - Patologia Generale e Anatomia Patologica Veterinaria
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/845241
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