Background: Tuberculosis (TB) unevenly affects individuals across the globe, especially in rural areas of low-income countries. Aim of the study was to assess the impact of social protection to increase TB awareness on treatment outcomes among TB patients in a rural area of Senegal. Materials & methods: The study, conducted in Fimela district (Senegal) from 1 January 2010to 31 December2019 and the intervention started from 31 January2013, includes activities to increase awareness, active case finding, active follow-upand social protection. Results: Overall, 435 subjects - mainly male and young-were included in the analysis. Among TB cases, 94% had pulmonary involvement, 87% had no previous TB history, and 6% resulted positiveHIV. Improved outcome was observed once intervention began (from 71to 91%, p<0.001); whereas mortality decreased (from 15 to 5%; p<0.001), especially for those HIV co-infected for whom TB mortality rate dropped from 70 to 29%. Conclusion: After beginning the cooperation program, TB treatment success increased as a result of the decline of mortality, especially in people living with HIV.

Tuberculosis treatment outcome in a rural area of Senegal : a decade of experience from 2010 to 2019 by StopTB Italia / N. Riccardi, S. Villa, A. Giacomelli, M. M Diaw, M. Ndiaye, L. Gning, M. Robbiano, R. Alagna, L. Saderi, A. Di Biagio, M. Bassetti, D. M Cirillo, G. Sotgiu, L. R Codecasa, M. Sarr, G. Besozzi. - In: FUTURE MICROBIOLOGY. - ISSN 1746-0913. - 16:6(2021 Apr), pp. 399-407.

Tuberculosis treatment outcome in a rural area of Senegal : a decade of experience from 2010 to 2019 by StopTB Italia

S. Villa
;
A. Giacomelli;
2021-04

Abstract

Background: Tuberculosis (TB) unevenly affects individuals across the globe, especially in rural areas of low-income countries. Aim of the study was to assess the impact of social protection to increase TB awareness on treatment outcomes among TB patients in a rural area of Senegal. Materials & methods: The study, conducted in Fimela district (Senegal) from 1 January 2010to 31 December2019 and the intervention started from 31 January2013, includes activities to increase awareness, active case finding, active follow-upand social protection. Results: Overall, 435 subjects - mainly male and young-were included in the analysis. Among TB cases, 94% had pulmonary involvement, 87% had no previous TB history, and 6% resulted positiveHIV. Improved outcome was observed once intervention began (from 71to 91%, p<0.001); whereas mortality decreased (from 15 to 5%; p<0.001), especially for those HIV co-infected for whom TB mortality rate dropped from 70 to 29%. Conclusion: After beginning the cooperation program, TB treatment success increased as a result of the decline of mortality, especially in people living with HIV.
mycobacterium tuberculosis; rural area; social protection; treatment outcome; tuberculosis
Settore MED/17 - Malattie Infettive
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/839272
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