Cardiac amyloidosis is a serious and progressive infiltrative disease that is caused by the deposition of amyloid fibrils at the cardiac level. It can be due to rare genetic variants in the hereditary forms or as a consequence of acquired conditions. Thanks to advances in imaging techniques and the possibility of achieving a non-invasive diagnosis, we now know that cardiac amyloidosis is a more frequent disease than traditionally considered. In this position paper the Working Group on Myocardial and Pericardial Disease proposes an invasive and non-invasive definition of cardiac amyloidosis, addresses clinical scenarios and situations to suspect the condition and proposes a diagnostic algorithm to aid diagnosis. Furthermore, we also review how to monitor and treat cardiac amyloidosis, in an attempt to bridge the gap between the latest advances in the field and clinical practice.

Diagnosis and treatment of cardiac amyloidosis. A position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases / P. Garcia‐Pavia, C. Rapezzi, Y. Adler, M. Arad, C. Basso, A. Brucato, I. Burazor, A.L.P. Caforio, T. Damy, U. Eriksson, M. Fontana, J.D. Gillmore, E. Gonzalez‐Lopez, M. Grogan, S. Heymans, M. Imazio, I. Kindermann, A.V. Kristen, M.S. Maurer, G. Merlini, A. Pantazis, S. Pankuweit, A.G. Rigopoulos, A. Linhart. - In: EUROPEAN JOURNAL OF HEART FAILURE. - ISSN 1388-9842. - (2021). [Epub ahead of print]

Diagnosis and treatment of cardiac amyloidosis. A position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases

A. Brucato;
2021

Abstract

Cardiac amyloidosis is a serious and progressive infiltrative disease that is caused by the deposition of amyloid fibrils at the cardiac level. It can be due to rare genetic variants in the hereditary forms or as a consequence of acquired conditions. Thanks to advances in imaging techniques and the possibility of achieving a non-invasive diagnosis, we now know that cardiac amyloidosis is a more frequent disease than traditionally considered. In this position paper the Working Group on Myocardial and Pericardial Disease proposes an invasive and non-invasive definition of cardiac amyloidosis, addresses clinical scenarios and situations to suspect the condition and proposes a diagnostic algorithm to aid diagnosis. Furthermore, we also review how to monitor and treat cardiac amyloidosis, in an attempt to bridge the gap between the latest advances in the field and clinical practice.
Settore MED/09 - Medicina Interna
7-apr-2021
Article (author)
File in questo prodotto:
File Dimensione Formato  
ejhf.2140.pdf

accesso aperto

Tipologia: Publisher's version/PDF
Dimensione 9.21 MB
Formato Adobe PDF
9.21 MB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/832728
Citazioni
  • ???jsp.display-item.citation.pmc??? 23
  • Scopus 52
  • ???jsp.display-item.citation.isi??? 47
social impact