Background: Patients aged 65 years and older are not traditionally considered optimal candidates for subthalamic deep brain stimulation (STN-DBS), mainly for their presumed increased incidence of surgical complications. The aim of this study was to assess STN-DBS surgery safety in relation to age. Methods: A total of 107 consecutive patients undergoing bilateral STN-DBS at our institution between 2002 and 2014 were retrospectively stratified according to age in two groups (Young group < 65 years old; Elderly group ≥ 65 years old;). Rate of short-term surgical complications (within 90 days) was reviewed and compared between the two groups. Results: Pre-operative baseline data were comparable between the two groups. The 90-days post-operative mortality rate was 0%. Overall incidence of complications related to surgery was 6,54%. In the Elderly group we observed 3 post-operative intra-cerebral haematomas (7,89%), 1 requiring urgent surgical evacuation. In the Young group we observed 2 post-operative asymptomatic intra-cerebral haematomas (2,89%) and 2 wound infections (2,89%), 1 requiring system removal. No others surgical complications were noticed in both groups. Conclusions: Chronological age ≥ 65 years old should not be considered alone as exclusion criteria to STN-DBS surgery.

"short term surgical complications after subthalamic deep brain stimulation for Parkinson's disease : Does old age matter?" Neurology, stroke and cognition / V. Levi, G. Carrabba, P. Rampini, M. Locatelli. - In: BMC GERIATRICS. - ISSN 1471-2318. - 15:1(2015), pp. 116.1-116.5. [10.1186/s12877-015-0112-2]

"short term surgical complications after subthalamic deep brain stimulation for Parkinson's disease : Does old age matter?" Neurology, stroke and cognition

V. Levi
;
G. Carrabba;M. Locatelli
2015

Abstract

Background: Patients aged 65 years and older are not traditionally considered optimal candidates for subthalamic deep brain stimulation (STN-DBS), mainly for their presumed increased incidence of surgical complications. The aim of this study was to assess STN-DBS surgery safety in relation to age. Methods: A total of 107 consecutive patients undergoing bilateral STN-DBS at our institution between 2002 and 2014 were retrospectively stratified according to age in two groups (Young group < 65 years old; Elderly group ≥ 65 years old;). Rate of short-term surgical complications (within 90 days) was reviewed and compared between the two groups. Results: Pre-operative baseline data were comparable between the two groups. The 90-days post-operative mortality rate was 0%. Overall incidence of complications related to surgery was 6,54%. In the Elderly group we observed 3 post-operative intra-cerebral haematomas (7,89%), 1 requiring urgent surgical evacuation. In the Young group we observed 2 post-operative asymptomatic intra-cerebral haematomas (2,89%) and 2 wound infections (2,89%), 1 requiring system removal. No others surgical complications were noticed in both groups. Conclusions: Chronological age ≥ 65 years old should not be considered alone as exclusion criteria to STN-DBS surgery.
Age; Complications; Deep brain stimulation; Parkinson's disease
Settore MED/27 - Neurochirurgia
Settore MED/26 - Neurologia
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/829100
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