Objective: To systematically review available evidence to develop guidelines for diag- nosis and treatment of transfusion-associated reactions in dogs and cats. Design: Standardized and systemic evaluation of the literature (identified through Medline via PubMed and Google Scholar searches) was carried out for identified transfusion reaction types in dogs and cats. The available evidence was evaluated using PICO (Population, Intervention, Comparison, Outcome) questions generated for each reaction type. The evidence was categorized by level of evidence (LOE) and quality (Good, Fair, or Poor). Guidelines, diagnostic, and treatment algorithms were gener- ated based on the evaluation of the evidence. Consensus on the final guidelines was achieved through Delphi-style surveys. Draft recommendations were disseminated through veterinary specialty listservs for review and comments, which were evaluated and integrated prior to final publication. Results: Medline via PubMed and Google Scholar databases were searched. There were 14 Population Intervention Comparison Outcome questions identified and corresponding worksheets were developed focusing on the diagnosis and treatment of transfusion-associated reactions in dogs and cats. Fourteen guidelines and four algo- rithms were developed with a high degree of consensus. Conclusions: This systematic evidence evaluation process yielded recommended diag- nostic and treatment algorithms for use in practice. However, significant knowledge gaps were identified, demonstrating the need for additional research in veterinary transfusion medicine.

Association of Veterinary Hematology and Transfusion Medicine (AVHTM) transfusion reaction small animal consensus statement (TRACS). Part 3 : Diagnosis and treatment / A. Odunayo, K.J. Nash, E.B. Davidow, S.L. Blois, I. Goy‐Thollot, L. Harris, K. Humm, S. Musulin, C.R. Sharp, E. Spada, J. Thomason, J. Walton, K. Jane Wardrop. - In: JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE. - ISSN 1479-3261. - 31:2(2021), pp. 189-203. [10.1111/vec.13043]

Association of Veterinary Hematology and Transfusion Medicine (AVHTM) transfusion reaction small animal consensus statement (TRACS). Part 3 : Diagnosis and treatment

E. Spada
Membro del Collaboration Group
;
2021

Abstract

Objective: To systematically review available evidence to develop guidelines for diag- nosis and treatment of transfusion-associated reactions in dogs and cats. Design: Standardized and systemic evaluation of the literature (identified through Medline via PubMed and Google Scholar searches) was carried out for identified transfusion reaction types in dogs and cats. The available evidence was evaluated using PICO (Population, Intervention, Comparison, Outcome) questions generated for each reaction type. The evidence was categorized by level of evidence (LOE) and quality (Good, Fair, or Poor). Guidelines, diagnostic, and treatment algorithms were gener- ated based on the evaluation of the evidence. Consensus on the final guidelines was achieved through Delphi-style surveys. Draft recommendations were disseminated through veterinary specialty listservs for review and comments, which were evaluated and integrated prior to final publication. Results: Medline via PubMed and Google Scholar databases were searched. There were 14 Population Intervention Comparison Outcome questions identified and corresponding worksheets were developed focusing on the diagnosis and treatment of transfusion-associated reactions in dogs and cats. Fourteen guidelines and four algo- rithms were developed with a high degree of consensus. Conclusions: This systematic evidence evaluation process yielded recommended diag- nostic and treatment algorithms for use in practice. However, significant knowledge gaps were identified, demonstrating the need for additional research in veterinary transfusion medicine.
anaphylaxis; corticosteroids; fever; hemolysis; transfusion reactions
Settore VET/08 - Clinica Medica Veterinaria
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/822207
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