The ongoing Corona Virus Disease 2019 (COVID–19) pandemic appears to increase risk for mental illness, either directly due to inflammation caused by the virus or indirectly due to related psychosocial stress, resulting in the development of both anxious-depressive and psychotic symptoms. The purpose of the present study was to assess the frequency and characteristics of all patients with First Episodes Psychosis (FEP) without COVID-19 infection hospitalized in the first four months since lockdown in Milan. We recruited sixty-two patients hospitalized between March 8 to July 8, 2020 versus those first hospitalized in the same period in 2019. The two subgroups were compared for sociodemographic variables and clinical characteristics of the episodes. Patients with FEP in 2020 were significantly older than patients with FEP in 2021, and presented with significantly less substances abuse. Interestingly, patients presenting with FEP in 2020 were significantly older than patients with FEP in 2019. These data are compatible with the greater vulnerability to stressful factors during the pandemic, as well as with the greater concern regarding a possible COVID-19 infection producing brain damage causing the FEP.

Impact of the first Covid-19 pandemic wave on first episode psychosis in Milan, italy / C.M. Esposito, A. D'Agostino, B. Dell Osso, A. Fiorentini, C. Prunas, A. Callari, L. Oldani, E. Fontana, G. Gargano, B. Viscardi, B. Giordano, S. D'Angelo, F. Wiedenmann, M. Macellaro, F. Giorgetti, N. Turtulici, O. Gambini, P. Brambilla. - In: PSYCHIATRY RESEARCH. - ISSN 0165-1781. - 298(2021 Apr). [10.1016/j.psychres.2021.113802]

Impact of the first Covid-19 pandemic wave on first episode psychosis in Milan, italy

C.M. Esposito
Primo
;
A. D'Agostino
Secondo
;
B. Dell Osso;A. Fiorentini;C. Prunas;L. Oldani;E. Fontana;G. Gargano;B. Viscardi;B. Giordano;S. D'Angelo;F. Wiedenmann;M. Macellaro;F. Giorgetti;O. Gambini
Penultimo
;
P. Brambilla
Ultimo
2021

Abstract

The ongoing Corona Virus Disease 2019 (COVID–19) pandemic appears to increase risk for mental illness, either directly due to inflammation caused by the virus or indirectly due to related psychosocial stress, resulting in the development of both anxious-depressive and psychotic symptoms. The purpose of the present study was to assess the frequency and characteristics of all patients with First Episodes Psychosis (FEP) without COVID-19 infection hospitalized in the first four months since lockdown in Milan. We recruited sixty-two patients hospitalized between March 8 to July 8, 2020 versus those first hospitalized in the same period in 2019. The two subgroups were compared for sociodemographic variables and clinical characteristics of the episodes. Patients with FEP in 2020 were significantly older than patients with FEP in 2021, and presented with significantly less substances abuse. Interestingly, patients presenting with FEP in 2020 were significantly older than patients with FEP in 2019. These data are compatible with the greater vulnerability to stressful factors during the pandemic, as well as with the greater concern regarding a possible COVID-19 infection producing brain damage causing the FEP.
Covid-19; SARS-CoV-2; First-Episode Psychosis; Brief Psychotic Episode; Reactive Psychosis;
Settore MED/25 - Psichiatria
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/821245
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