Purpose: Aim of study was to evaluate the differences in incidence and presentation of anorectal malformations (ARMs) between selected Pediatric Surgery Divisions in the Republic of South Africa (ZAR) and Italy. Methods: A retrospective cohort study involved analysis of clinical records of patients with ARM born between 2005 and 2012. Type of ARM, maternal age, birth weight, gestational age, presence of associated anomalies and delayed diagnosis were analyzed. Results: 335 patients were included in this study. Of note, statistically significant differences between the African and European patient groups were observed in a male predominance in the ZAR patient population. In addition, female recto-perineal fistulas were diagnosed in significantly more Italian patients than in ZAR. Furthermore, a more advanced maternal age and a lower gestational age was noted in the European cohort with a minimal delay in initial diagnosis as opposed to the African counterpart. Both centers reported recto-perineal fistula as the most common malformation in male patients. Conclusion: With the exception of perineal fistulas in females, the incidence of specific subtypes of ARMs was similar in the two groups. This may be of importance when extrapolating European study conclusion to the South African setting.

Comparison in the incidence of anorectal malformations between a first- and third-world referral center / A.P. Theron, G. Brisighelli, A.E. Theron, E. Leva, A. Numanoglu. - In: PEDIATRIC SURGERY INTERNATIONAL. - ISSN 0179-0358. - 31:8(2015 Aug), pp. 759-764. [10.1007/s00383-015-3740-x]

Comparison in the incidence of anorectal malformations between a first- and third-world referral center

E. Leva;
2015-08

Abstract

Purpose: Aim of study was to evaluate the differences in incidence and presentation of anorectal malformations (ARMs) between selected Pediatric Surgery Divisions in the Republic of South Africa (ZAR) and Italy. Methods: A retrospective cohort study involved analysis of clinical records of patients with ARM born between 2005 and 2012. Type of ARM, maternal age, birth weight, gestational age, presence of associated anomalies and delayed diagnosis were analyzed. Results: 335 patients were included in this study. Of note, statistically significant differences between the African and European patient groups were observed in a male predominance in the ZAR patient population. In addition, female recto-perineal fistulas were diagnosed in significantly more Italian patients than in ZAR. Furthermore, a more advanced maternal age and a lower gestational age was noted in the European cohort with a minimal delay in initial diagnosis as opposed to the African counterpart. Both centers reported recto-perineal fistula as the most common malformation in male patients. Conclusion: With the exception of perineal fistulas in females, the incidence of specific subtypes of ARMs was similar in the two groups. This may be of importance when extrapolating European study conclusion to the South African setting.
Anorectal malformation; Incidence; Italy; South Africa; Anal Canal; Anorectal Malformations; Anus, Imperforate; Cohort Studies; Female; Humans; Incidence; Infant, Newborn; Italy; Male; Pilot Projects; Rectum; Retrospective Studies; South Africa; Referral and Consultation
Settore MED/20 - Chirurgia Pediatrica e Infantile
Article (author)
File in questo prodotto:
File Dimensione Formato  
Theron2015_Article_ComparisonInTheIncidenceOfAnor.pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 378.78 kB
Formato Adobe PDF
378.78 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/811296
Citazioni
  • ???jsp.display-item.citation.pmc??? 4
  • Scopus 11
  • ???jsp.display-item.citation.isi??? 11
social impact