The analysis of complex protein samples can be time-consuming and expensive, due to the problems in identifying low abundance proteins in complex biological samples. We show that morphological source separation and multiscale filtering by wavelet transforms yield 2-DE gel images whose partial suppression of noise improves the spot detection phase from reconstructed serum maps.
Backing up 2-de depletion with source separation and wavelet decomposition methods / A. Soggiu, O. Marullo, E. Capobianco. - In: BIOPHYSICAL REVIEWS AND LETTERS. - ISSN 1793-0480. - 4:4(2009), pp. 319-330. [10.1142/S1793048009001071]
Backing up 2-de depletion with source separation and wavelet decomposition methods
A. Soggiu;
2009
Abstract
The analysis of complex protein samples can be time-consuming and expensive, due to the problems in identifying low abundance proteins in complex biological samples. We show that morphological source separation and multiscale filtering by wavelet transforms yield 2-DE gel images whose partial suppression of noise improves the spot detection phase from reconstructed serum maps.
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