The process of DNA replication is threatened by many factors, including DNA lesions, and machineries acting as obstacles. Here we discuss and speculate on a recently proposed mechanism of DNA damage response activation in response to lesions that challenge the progression of DNA replication forks.
A model of DNA damage response activation at stalled replication forks by SPRTN / C. Bruhn, M. Foiani. - In: NATURE COMMUNICATIONS. - ISSN 2041-1723. - 10:1(2019), pp. 5671.1-5671.3. [10.1038/s41467-019-13610-7]
A model of DNA damage response activation at stalled replication forks by SPRTN
M. Foiani
Ultimo
2019
Abstract
The process of DNA replication is threatened by many factors, including DNA lesions, and machineries acting as obstacles. Here we discuss and speculate on a recently proposed mechanism of DNA damage response activation in response to lesions that challenge the progression of DNA replication forks.
File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
s41467-019-13610-7(1).pdf
accesso aperto
Tipologia:
Publisher's version/PDF
Dimensione
322.12 kB
Formato
Adobe PDF
|
322.12 kB | Adobe PDF | Visualizza/Apri |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
