Objective.To establish optimal cut-off values for the scores of the revised Fibromyalgia Impact Questionnaire(FIQR), the modified Fibromialgia Assessment Scale (FAS 2019mod), and the Polysymptomatic Distress Scale (PDS)in order to distinguish five levels of FM disease severity.Methods.Consecutive FM patients were evaluated with the three clinimetric indices, and each patient wasrequired to answer the anchor question: ‘In general, would you say your health is 1¼very good, 2¼good, 3¼fair,4¼poor, or 5¼very poor?’—which represented the external criterion. Cut-off points were established through theinterquartile reconciliation approach.Results.The study sample consisted of 2181 women (93.2%) and 158 men (6.8%), with a mean age of 51.9(11.5)years, and mean disease duration was 7.3 (6.9) years. The overall median FIQR, FAS 2019 mod and PDSscores (25th–75th percentiles) were respectively 61.16 (41.16–77.00), 27.00 (19.00–32.00) and 19.0 (13.00–24.00).Reconciliation of the mean 75th and 25th percentiles of adjacent categories defined the severity states for FIQR:0–23 for remission, 24–40 for mild disease, 41–63 for moderate disease, 64–82 for severe disease and>83 forvery severe disease; FAS 2019 mod: 0–12 for remission, 13–20 for mild disease, 21–28 for moderate disease, 29–33 for severe disease and>33 for very severe disease; PDS: 0–5 for remission, 6–15 for mild disease, 16–20 formoderate disease, 21–25 for severe disease and>25 for very severe disease. Conclusions.Disease severity cut-offs can represent an important improvement in interpreting FM.

Definition of fibromyalgia severity: findings from a cross-sectional survey of 2339 Italian patients / F. Salaffi, M. Di Carlo, L. Bazzichi, F. Atzeni, M. Govoni, G. Biasi, M. Di Franco, F. Mozzani, E. Gremese, L. Dagna, A. Batticciotto, F. Fischetti, R. Giacomelli, S. Guiducci, G. Guggino, M. Bentivegna, R. Gerli, C. Salvarani, G. Bajocchi, M. Ghini, F. Iannone, V. Giorgi, S. Farah, M. Cirillo, S. Bonazza, S. Barbagli, C. Gioia, D. Santilli, A. Capacci, G. Cavalli, F. Carubbi, F. Nacci, I. Riccucci, L. Sinigaglia, M. Masullo, B. Polizzi, M. Cutolo, P. Sarzi-Puttini. - In: RHEUMATOLOGY. - ISSN 1462-0324. - 60:2(2021 Feb 01), pp. keaa355.728-keaa355.736. [10.1093/rheumatology/keaa355]

Definition of fibromyalgia severity: findings from a cross-sectional survey of 2339 Italian patients

F. Atzeni;G. Biasi;A. Batticciotto;R. Giacomelli;F. Iannone;C. Gioia;G. Cavalli;P. Sarzi-Puttini
Ultimo
2021

Abstract

Objective.To establish optimal cut-off values for the scores of the revised Fibromyalgia Impact Questionnaire(FIQR), the modified Fibromialgia Assessment Scale (FAS 2019mod), and the Polysymptomatic Distress Scale (PDS)in order to distinguish five levels of FM disease severity.Methods.Consecutive FM patients were evaluated with the three clinimetric indices, and each patient wasrequired to answer the anchor question: ‘In general, would you say your health is 1¼very good, 2¼good, 3¼fair,4¼poor, or 5¼very poor?’—which represented the external criterion. Cut-off points were established through theinterquartile reconciliation approach.Results.The study sample consisted of 2181 women (93.2%) and 158 men (6.8%), with a mean age of 51.9(11.5)years, and mean disease duration was 7.3 (6.9) years. The overall median FIQR, FAS 2019 mod and PDSscores (25th–75th percentiles) were respectively 61.16 (41.16–77.00), 27.00 (19.00–32.00) and 19.0 (13.00–24.00).Reconciliation of the mean 75th and 25th percentiles of adjacent categories defined the severity states for FIQR:0–23 for remission, 24–40 for mild disease, 41–63 for moderate disease, 64–82 for severe disease and>83 forvery severe disease; FAS 2019 mod: 0–12 for remission, 13–20 for mild disease, 21–28 for moderate disease, 29–33 for severe disease and>33 for very severe disease; PDS: 0–5 for remission, 6–15 for mild disease, 16–20 formoderate disease, 21–25 for severe disease and>25 for very severe disease. Conclusions.Disease severity cut-offs can represent an important improvement in interpreting FM.
fibromyalgia; severity; cut-off points; revised Fibromyalgia Impact Questionnaire; modified;Fibromyalgia Assessment Status; polysymptomatic distress scale;
Settore MED/16 - Reumatologia
1-feb-2021
13-ago-2020
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/801563
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