Inflammatory bowel disease (IBDs), including the two main subtypes of Crohn's disease and ulcerative colitis, not only affects the gastrointestinal system, but also has a wide range of extra-intestinal manifestations (EIMs) that are major sources of morbidity and disability, and therefore represent what can be considered a real syndrome. The pathogenetic mechanisms underlying these EIMs are unknown, but some may share a common pathogenesis with IBD and others may be due to IBD treatment. The aim of this review is to examine our current knowledge of IBD EIMs and their treatment.
Extra-intestinal manifestations of inflammatory bowel diseases / D. Marotto, F. Atzeni, S. Ardizzone, G. Monteleone, V. Giorgi, P. Sarzi-Puttini. - In: PHARMACOLOGICAL RESEARCH. - ISSN 1043-6618. - 161:(2020 Nov). [10.1016/j.phrs.2020.105206]
Extra-intestinal manifestations of inflammatory bowel diseases
S. Ardizzone;P. Sarzi-PuttiniUltimo
2020
Abstract
Inflammatory bowel disease (IBDs), including the two main subtypes of Crohn's disease and ulcerative colitis, not only affects the gastrointestinal system, but also has a wide range of extra-intestinal manifestations (EIMs) that are major sources of morbidity and disability, and therefore represent what can be considered a real syndrome. The pathogenetic mechanisms underlying these EIMs are unknown, but some may share a common pathogenesis with IBD and others may be due to IBD treatment. The aim of this review is to examine our current knowledge of IBD EIMs and their treatment.
| File | Dimensione | Formato | |
|---|---|---|---|
|
1-s2.0-S1043661820315140-main.pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Dimensione
561.54 kB
Formato
Adobe PDF
|
561.54 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
