Introduction: The COVID-19 pandemic caused an increased mortality in nursing homes due to its quickspreadand the age-related high lethality.Results: We observed a two-month mortality of 40%, compared to 6.4% in the previous year. This increasewasseen in both COVID-19 positive (43%) and negative (24%) residents, but 8 patients among thosetestingnegative on the swab, tested positive on serological tests. Increased mortality was associated withmalegender, older age, no previous vitamin D supplementation and worse “activities of daily living (ADL)”scores,such as Barthel index, Tinetti scale and S.OS.I.A. classification.Conclusion: Our data confirms a higher geriatric mortality due to COVID-19. Negative residents also had highermortality, which we suspect is secondary to preanalytical error and a low sensitivity of the swab test in poorlycompliant subjects. Male gender, older age and low scores on ADL scales (probably due to immobility) areriskfactors for COVID-19 related mortality. Finally, mortality was inversely associated with vitaminDsupplementation.Design: In this observational study, we described the two-month mortality among the 157 residents (age 60-100) of a nursing home after Sars-CoV-2 spreading, reporting the factors associated with the outcome. Wealsocompared the diagnostic tests for Sars-CoV-2.
Mortality in an italian nursing home during COVID-19 pandemic: correlation with gender, age, ADL, vitamin D supplementation, and limitations of the diagnostic tests / B. Cangiano, L.M. Fatti, L. Danesi, G. Gazzano, M. Croci, G. Vitale, L. Gilardini, S. Bonadonna, I. Chiodini, C.F. Caparello, A. Conti, L. Persani, M. Stramba-Badiale, M. Bonomi. - In: AGING. - ISSN 1945-4589. - 12:24(2020 Dec 22), pp. 24522-24534.
|Titolo:||Mortality in an italian nursing home during COVID-19 pandemic: correlation with gender, age, ADL, vitamin D supplementation, and limitations of the diagnostic tests|
CANGIANO, BIAGIO (Co-primo)
BONOMI, MARCO (Ultimo) (Corresponding)
|Parole Chiave:||hydroxychloroquine, serology, nasopharyngeal swab, sensitivity and specificity, activities of daily living, COVID-19|
|Settore Scientifico Disciplinare:||Settore MED/13 - Endocrinologia|
Settore MED/09 - Medicina Interna
|Data di pubblicazione:||22-dic-2020|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.18632/aging.202307|
|Appare nelle tipologie:||01 - Articolo su periodico|