We retrospectively investigated, in 62 consecutive hospitalised COVID-19 patients (aged 70 ± 14 years, 40 males), the prognostic value of CT-derived subcutaneous adipose tissue and visceral adipose tissue (VAT) metrics, testing them in four predictive models for admission to intensive care unit (ICU), with and without pre-existing comorbidities. Multivariate logistic regression identified VAT score as the best ICU admission predictor (odds ratios 4.307–12.842). A non-relevant contribution of comorbidities at receiver operating characteristic analysis (area under the curve 0.821 for the CT-based model, 0.834 for the one including comorbidities) highlights the potential one-stop-shop prognostic role of CT-derived lung and adipose tissue metrics.
Visceral adipose tissue area predicts intensive care unit admission in COVID-19 patients / F. Pediconi, V. Rizzo, S. Schiaffino, A. Cozzi, G. DELLA PEPA, F. Galati, C. Catalano, F. Sardanelli. - In: OBESITY RESEARCH & CLINICAL PRACTICE. - ISSN 1871-403X. - (2020). [Epub ahead of print] [10.1016/j.orcp.2020.12.002]
Visceral adipose tissue area predicts intensive care unit admission in COVID-19 patients
A. Cozzi;G. DELLA PEPA;F. SardanelliUltimo
2020
Abstract
We retrospectively investigated, in 62 consecutive hospitalised COVID-19 patients (aged 70 ± 14 years, 40 males), the prognostic value of CT-derived subcutaneous adipose tissue and visceral adipose tissue (VAT) metrics, testing them in four predictive models for admission to intensive care unit (ICU), with and without pre-existing comorbidities. Multivariate logistic regression identified VAT score as the best ICU admission predictor (odds ratios 4.307–12.842). A non-relevant contribution of comorbidities at receiver operating characteristic analysis (area under the curve 0.821 for the CT-based model, 0.834 for the one including comorbidities) highlights the potential one-stop-shop prognostic role of CT-derived lung and adipose tissue metrics.File | Dimensione | Formato | |
---|---|---|---|
1-s2.0-S1871403X20306219-main.pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Dimensione
674.38 kB
Formato
Adobe PDF
|
674.38 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.