The ganglioside pattern from normal human temporal cortex and cerebellum has been studied in fresh specimens obtained at surgery.The analyses have been performed by two-dimensional thin layer chromatography with an intermediate ammonia treatment which is a methodology particularly suitable for resolving alkali labile gangliosides.Alkali labile gangliosides were detected in all the analyzed specimens and their content contributed to 23% and 11% of total lipid bound sialic acid, in temporal cortex and cerebellum, respectively.

Ganglioside pattern of normal human brain, from samples obtained at surgery : A study especially referred to alkali labile species / L. Riboni, A. Malesci, S.M. Gaini, S. Sonnino, R. Ghidoni, G. Tettamanti. - In: JOURNAL OF BIOCHEMISTRY. - ISSN 0021-924X. - 96:6(1984), pp. 1943-1946. [10.1093/oxfordjournals.jbchem.a135030]

Ganglioside pattern of normal human brain, from samples obtained at surgery : A study especially referred to alkali labile species

L. Riboni;A. Malesci;S.M. Gaini;S. Sonnino;R. Ghidoni;G. Tettamanti
1984

Abstract

The ganglioside pattern from normal human temporal cortex and cerebellum has been studied in fresh specimens obtained at surgery.The analyses have been performed by two-dimensional thin layer chromatography with an intermediate ammonia treatment which is a methodology particularly suitable for resolving alkali labile gangliosides.Alkali labile gangliosides were detected in all the analyzed specimens and their content contributed to 23% and 11% of total lipid bound sialic acid, in temporal cortex and cerebellum, respectively.
Settore BIO/10 - Biochimica
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/800207
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