Antihypertensive drug treatment has been shown to significantly decrease cardiovascular morbidity and mortality rates in hypertensive subjects and to reduce the occurrence of major hypertension-related complications, such as stroke, coronary artery disease, congestive heart failure and renal insufficiency. Despite these favorable effects, several issues related to antihypertensive treatment remain to be clarified. This paper will discuss some of these issues, with particular reference to the effects of blood pressure lowering on renal diseases and coronary heart disease. It will also discuss the ongoing clinical trials aimed at clarifying some unsolved issues of antihypertensive treatment. The objective of the International Nifedipine GITS Study Intervention as a Goal in Hypertensive Treatment was to provide information on the effects of calcium antagonist treatment on high blood pressure values and on hypertension-related cardiovascular complications in a high-risk hypertensive population.

Primary Prevention of Cardiovascular Disease / G. Mancia, S. Carugo, G. Grassi. - In: CARDIOLOGY. - ISSN 0008-6312. - 88:3(1997), pp. 32-37. ((Intervento presentato al 3. convegno International Symposium on Long-Acting Nifedipine tenutosi a Berlin nel 1996 [10.1159/000177504].

Primary Prevention of Cardiovascular Disease

S. Carugo;
1997

Abstract

Antihypertensive drug treatment has been shown to significantly decrease cardiovascular morbidity and mortality rates in hypertensive subjects and to reduce the occurrence of major hypertension-related complications, such as stroke, coronary artery disease, congestive heart failure and renal insufficiency. Despite these favorable effects, several issues related to antihypertensive treatment remain to be clarified. This paper will discuss some of these issues, with particular reference to the effects of blood pressure lowering on renal diseases and coronary heart disease. It will also discuss the ongoing clinical trials aimed at clarifying some unsolved issues of antihypertensive treatment. The objective of the International Nifedipine GITS Study Intervention as a Goal in Hypertensive Treatment was to provide information on the effects of calcium antagonist treatment on high blood pressure values and on hypertension-related cardiovascular complications in a high-risk hypertensive population.
hypertension; antihypertensive treatment; cardiovascular morbidity; cardiovascular mortality; calcium antagonists; clinical trials
Settore MED/11 - Malattie dell'Apparato Cardiovascolare
1997
Article (author)
File in questo prodotto:
File Dimensione Formato  
cardiology 1997.pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 644.52 kB
Formato Adobe PDF
644.52 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/796276
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 3
social impact