The use of transcranial magnetic stimulation (TMS) for Obsessive- compulsive disorder (OCD)

We here describe a case of major depressive disorder in comorbidity with a hoarding disorder, treated with repetitive transcranial magnetic stimulation (rTMS). The patient was a 59-year-old woman with a treatment-resistant depression and a history of hoarding disorder. She had been treated with several antidepressants, belonging to different classes, with a partial or none response. The patient underwent a protocol of stimulation with high-frequency rTMS (10 Hz, 20 sessions, 1 session per day), on the left dorsolateral prefrontal cortex, 750 stimuli per session, in augmentation to the pharmacological treatment. We observed an improvement in both OCD and depressive symptoms. The rTMS had been well tolerated by the patient who did not report any side effects. In conclusion, the present clinical report shows the efficacy of rTMS in a patient with OCD in comorbidity with treatment-resistant depression.