In this paper, we propose an absolutely innovative technique for the electrical stimulation of cells, based on piezoelectric nanoparticles. Ultrasounds are used to impart mechanical stress to boron nitride nanotubes incubated with neuronal-like PC12 cells. By virtue of their piezoelectric properties, these nanotubes can polarize and convey electrical stimuli to the cells. PC12 stimulated with the present method exhibit neurite sprout 30% greater than the control cultures after 9 days of treatment.
Enhancement of neurite outgrowth in neuronal-like cells following boron nitride nanotube-mediated stimulation / G. Ciofani, S. Danti, D. D'Alessandro, L. Ricotti, S. Moscato, G. Bertoni, A. Falqui, S. Berrettini, M. Petrini, V. Mattoli, A. Menciassi. - In: ACS NANO. - ISSN 1936-0851. - 4:10(2010 Oct), pp. 6267-6277. [10.1021/nn101985a]
Enhancement of neurite outgrowth in neuronal-like cells following boron nitride nanotube-mediated stimulation
A. Falqui;
2010
Abstract
In this paper, we propose an absolutely innovative technique for the electrical stimulation of cells, based on piezoelectric nanoparticles. Ultrasounds are used to impart mechanical stress to boron nitride nanotubes incubated with neuronal-like PC12 cells. By virtue of their piezoelectric properties, these nanotubes can polarize and convey electrical stimuli to the cells. PC12 stimulated with the present method exhibit neurite sprout 30% greater than the control cultures after 9 days of treatment.File | Dimensione | Formato | |
---|---|---|---|
Enhancement of Neurite Outgrowth in Neuronal-Like Cells following Boron Nitride Nanotube-Mediated Stimulation ACS NANO.pdf
accesso riservato
Descrizione: Articolo principale
Tipologia:
Publisher's version/PDF
Dimensione
6.57 MB
Formato
Adobe PDF
|
6.57 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.