An international, expert led consensus initiative was set up by the Collaborative Ocular Tuberculosis Study (COTS) group to develop systematic, evidence, and experience-based recommendations for the treatment of ocular TB using a modified Delphi technique process. In the first round of Delphi, the group identified clinical scenarios pertinent to ocular TB based on five clinical phenotypes (anterior uveitis, intermediate uveitis, choroiditis, retinal vasculitis, and panuveitis). Using an interactive online questionnaires, guided by background knowledge from published literature, 486 consensus statements for initiating ATT were generated and deliberated amongst 81 global uveitis experts. The median score of five was considered reaching consensus for initiating ATT. The median score of four was tabled for deliberation through Delphi round 2 in a face-to-face meeting. This report describes the methodology adopted and followed through the consensus process, which help elucidate the guidelines for initiating ATT in patients with choroidal TB.

The Collaborative Ocular Tuberculosis Study (COTS) Consensus (CON) Group Meeting Proceedings / R. Agrawal, I. Testi, S. Mahajan, Y.S. Yuen, A. Agarwal, A. Rousselot, D. Raje, D.V. Gunasekeran, O.M. Kon, T. Barisani-Asenbauer, J.H. Kempen, A. Gupta, D.A. Jabs, J.R. Smith, B. Bodaghi, M. Zierhut, M. DeSmet, P.M. Cluskey, M. Agarwal, M. Agarwal, K. Aggarwal, M. Agrawal, H. Al-Dhibi, S. Androudi, F. Asyari, M.B. Balasundaram, K.B. Murthy, E. Baglivo, A. Banker, R. Bansal, S. Basu, D. Behera, J. Biswas, E. Carreno, L. Caspers, S.P. Chee, R. Chhabra, L. Cimino, L.E.C. del Rio, E.T. Cunningham, A.L.L. Curi, D. Das, E. Denisova, A.K. Denniston, M.-. Errera, A. Fonollosa, A. George, D.A. Goldstein, Y.G. Crosier, A. Gurbaxani, A. Invernizzi, H.M. Isa, d.I.S. M, N. Jones, D. Katoch, M. Khairallah, A. Khosla, M. Kramer, A. Kumar, A. Kumar, R.L.D. Nora, R. Lee, C. Lowder, S. Luthra, P. Mahendradas, D. Makhoul, S. Mazumdar, S. Mehta, E. Miserocchi, M. Mochizuki, O.S. Mohamed, C. Muccioli, M.R. Munk, S. Murthy, S. Narain, H. Nascimento, P. Neri, M. Nguyen, A.A. Okada, P. Ozdal, A. Palestine, F. Pichi, S.R. Rathinam, A. Schlaen, S. Sehgal, H.N. Sen, A. Sharma, K. Sharma, S.S. Shoughy, N. Singh, R. Singh, M. Soheilian, S. Sridharan, J.E. Thorne, C. Tappeiner, S. Teoh, M.S. Tognon, I. Tugal-Tutkun, M. Tyagi, H. Uy, D.V.V. Santos, N.V. Valentincic, M. Westcott, R. Yanai, B.Y. Alvarez, R. Zahedur, Q.D. Nguyen, C. Pavesio, V. Gupta. - In: OCULAR IMMUNOLOGY AND INFLAMMATION. - ISSN 0927-3948. - (2020). [Epub ahead of print] [10.1080/09273948.2020.1716025]

The Collaborative Ocular Tuberculosis Study (COTS) Consensus (CON) Group Meeting Proceedings

A. Invernizzi;F. Pichi;
2020

Abstract

An international, expert led consensus initiative was set up by the Collaborative Ocular Tuberculosis Study (COTS) group to develop systematic, evidence, and experience-based recommendations for the treatment of ocular TB using a modified Delphi technique process. In the first round of Delphi, the group identified clinical scenarios pertinent to ocular TB based on five clinical phenotypes (anterior uveitis, intermediate uveitis, choroiditis, retinal vasculitis, and panuveitis). Using an interactive online questionnaires, guided by background knowledge from published literature, 486 consensus statements for initiating ATT were generated and deliberated amongst 81 global uveitis experts. The median score of five was considered reaching consensus for initiating ATT. The median score of four was tabled for deliberation through Delphi round 2 in a face-to-face meeting. This report describes the methodology adopted and followed through the consensus process, which help elucidate the guidelines for initiating ATT in patients with choroidal TB.
Antitubercular therapy; choroiditis; Collaborative Ocular Tuberculosis Study Consensus (COTS CON); consensus guidelines; ocular tuberculosis
Settore MED/30 - Malattie Apparato Visivo
apr-2020
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/773908
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