Elevated troponin in patients with coronavirus disease 2019: possible mechanisms

Coronavirus disease 2019 (COVID-19) is a pandemic that has affected more than 1.8 million people world-wide, overwhelmed health care systems owing to the high proportion of critical presentations, and resultedin more than 100,000 deaths. Since the first data analyses in China, elevated cardiac troponin has beennoted in a substantial proportion of patients, implicating myocardial injury as a possible pathogenic mecha-nism contributing to severe illness and mortality. Accordingly, high troponin levels are associated withincreased mortality in patients with COVID-19. This brief review explores the available evidence regardingthe association between COVID-19 and myocardial injury.