Seasonality of acute viral respiratory diseases is a well-known and yet not fully understood phenomenon. Several models have been proposed to explain the regularity of yearly recurring outbreaks and the phase-differences observed at different latitudes on Earth. Such models consider known internal causes, primarily the periodic emergence of new virus variants that evade the host immune response. Yet, this alone, is generally unable to explain the regularity of recurrences and the observed phase-differences. Here we show that seasonality of viral respiratory diseases, as well as its distribution with latitude on Earth, can be fully explained by the virucidal properties of UV-B and A Solar photons through a daily, minute-scale, resonant forcing mechanism. Such an induced periodicity can last, virtually unperturbed, from tens to hundreds of cycles, and even in presence of internal dynamics (host's loss of immunity) much slower than seasonal will, on a long period, generate seasonal oscillations.
Forcing Seasonality of influenza-like epidemics with daily Solar resonance / F. Nicastro, G. Sironi, E. Antonello, A. Bianco, M. Biasin, J.R. Brucato, I. Ermolli, G. Pareschi, M. Salvati, P. Tozzi, D. Trabattoni, M. Clerici. - In: ISCIENCE. - ISSN 2589-0042. - (2020).
|Titolo:||Forcing Seasonality of influenza-like epidemics with daily Solar resonance|
|Settore Scientifico Disciplinare:||Settore BIO/13 - Biologia Applicata|
Settore MED/05 - Patologia Clinica
|Data di pubblicazione:||2020|
|Data ahead of print / Data di stampa:||24-set-2020|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.isci.2020.101605|
|Appare nelle tipologie:||01 - Articolo su periodico|