Pulmonary hypertension related to chronic lung disease, mainly represented by COPD and idiopathic pulmonary fibrosis, is associated with a worse outcome when compared with patients only affected by parenchymal lung disease. At present, no therapies are available to reverse or slow down the pathological process of this condition and most of the clinical trials conducted to date have had no clinically significant impact. Nevertheless, the importance of chronic lung diseases is always more widely recognised and, along with its increasing incidence, associated pulmonary hypertension is also expected to be growing in frequency and as a health burden worldwide. Therefore, it is desirable to develop useful and reliable tools to obtain an early diagnosis and to monitor and follow-up this condition, while new insights in the therapeutic approach are explored.

Pulmonary hypertension and chronic lung disease : where are we headed? / D. Elia, A. Caminati, M. Zompatori, R. Cassandro, C. Lonati, F. Luisi, G. Pelosi, S. Provencher, S. Harari. - In: EUROPEAN RESPIRATORY REVIEW. - ISSN 0905-9180. - 28:153(2019), pp. 190065.1-190065.14. [10.1183/16000617.0065-2019]

Pulmonary hypertension and chronic lung disease : where are we headed?

G. Pelosi;S. Harari
2019

Abstract

Pulmonary hypertension related to chronic lung disease, mainly represented by COPD and idiopathic pulmonary fibrosis, is associated with a worse outcome when compared with patients only affected by parenchymal lung disease. At present, no therapies are available to reverse or slow down the pathological process of this condition and most of the clinical trials conducted to date have had no clinically significant impact. Nevertheless, the importance of chronic lung diseases is always more widely recognised and, along with its increasing incidence, associated pulmonary hypertension is also expected to be growing in frequency and as a health burden worldwide. Therefore, it is desirable to develop useful and reliable tools to obtain an early diagnosis and to monitor and follow-up this condition, while new insights in the therapeutic approach are explored.
Animals; Early Diagnosis; Humans; Incidence; Prevalence; Prognosis; Risk Assessment; Risk Factors; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Pulmonary Disease, Chronic Obstructive
Settore MED/10 - Malattie dell'Apparato Respiratorio
2019
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/765613
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