Proteins of different regions of the Hirudo medicinalis central nervous system have been analyzed by means of two-dimensional electrophoresis. 2. Subcellular distribution of phosphoproteins has been studied in leech segmental ganglia. 3. Phorbol 12,13-dibutyrate, a protein kinase C activator, stimulates the phosphorylation of a number of proteins whose isoelectric points and mol. wts are presented. 4. Putative roles for these phosphoproteins are discussed.
Effects of Phorbol Ester on protein phosphorylation in the central nervous system of the Leech Hirudo medicinalis : a two dimensional electrophoretical analysis / M. Garcia-Gil, D. Bottai, M. Canizzaro, M. Brunelli. - In: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. B, COMPARATIVE BIOCHEMISTRY. - ISSN 0305-0491. - 99:4(1991), pp. 859-864.
Effects of Phorbol Ester on protein phosphorylation in the central nervous system of the Leech Hirudo medicinalis : a two dimensional electrophoretical analysis
D. BottaiSecondo
;
1991
Abstract
Proteins of different regions of the Hirudo medicinalis central nervous system have been analyzed by means of two-dimensional electrophoresis. 2. Subcellular distribution of phosphoproteins has been studied in leech segmental ganglia. 3. Phorbol 12,13-dibutyrate, a protein kinase C activator, stimulates the phosphorylation of a number of proteins whose isoelectric points and mol. wts are presented. 4. Putative roles for these phosphoproteins are discussed.
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