We analysed 5,484 close contacts of coronavirus disease (COVID-19) cases in Italy, all tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infection fatality ratio was 0.43% (95% confidence interval (CI): 0.21-0.79) for individuals younger than 70 years and 10.5% (95% CI: 8.0-13.6) for older individuals. Risk of death after infection was 62% lower (95% CI: 31-80) in clusters identified after 16 March 2020 and 1.8-fold higher for males (95% CI: 1.03-3.16).
Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020 / P. Poletti, M. Tirani, D. Cereda, F. Trentini, G. Guzzetta, V. Marziano, S. Buoro, S. Riboli, L. Crottogini, R. Piccarreta, A. Piatti, G. Grasselli, A. Melegaro, M. Gramegna, M. Ajelli, S. Merler. - In: EUROSURVEILLANCE. - ISSN 1560-7917. - 25:31(2020 Aug 06), pp. PII 2001383.2-PII 2001383.7. [10.2807/1560-7917.ES.2020.25.31.2001383]
Age-specific SARS-CoV-2 infection fatality ratio and associated risk factors, Italy, February to April 2020
G. Grasselli;
2020
Abstract
We analysed 5,484 close contacts of coronavirus disease (COVID-19) cases in Italy, all tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infection fatality ratio was 0.43% (95% confidence interval (CI): 0.21-0.79) for individuals younger than 70 years and 10.5% (95% CI: 8.0-13.6) for older individuals. Risk of death after infection was 62% lower (95% CI: 31-80) in clusters identified after 16 March 2020 and 1.8-fold higher for males (95% CI: 1.03-3.16).
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