Relevant non‐pharmacologic topics for clinical research in rheumatic musculoskeletal diseases: The patient perspective

Objective: The research approach on rheumatic musculoskeletal diseases (RMDs) is challenging and patient involvement is an emerging issue to obtain relevant informa-tion to research. Despite growing interest in non-pharmacologic aspects of clinical research in RMDs, the patients’ perspectives are currently poorly explored.Methods: A cross-sectional no-profit online survey was devised to identify and rank the priorities for clinical research in RMDs according to patients’ perspectives. Patients were asked to rate the following topics: food/nutrition, air pollution, smok-ing, work activity, social participation, physical activity, emotional well-being/stress, alternative medicine, and patient-physician relationship. The survey was dissemi-nated by ALOMAR (Lombard Association for Rheumatic Diseases) between June and October 2019.Results: Two hundred RMD patients completed the survey. The topic most rated 188 (94%) was the doctor-patient relationship, considered very or extremely important. Other topics rated as follows: psychological well-being 185 (92.5%), physical activity 155 (77.5%), nutrition, eating habits 150 (75%), alternative therapies 144 (72%), work activity 144 (72%), environmental pollution 134 (67%), social life 121 (60.5%) and cigarette smoke 119 (59.5%). The topics considered relevant were perceived to be able to influence disease symptoms. Environmental pollution and smoking were con-sidered the most important for RMD prevention in 43.3% and 48.7% respectively.Conclusions: This survey highlights the relevance of several unmet needs and indi-cates that active patient involvement is essential to design successful translational studies and improve clinical outcomes.