Background: Few case reports and clinical series exist on pregnant women infected with SARS-CoV-2 who delivered. Objective: To review the available information on mode of delivery, vertical/peripartum transmission, and neonatal outcome in pregnant women infected with SARS-CoV-2. Search strategy: Combination of the following key words: COVID-19, SARS-CoV-2, and pregnancy in Embase and PubMed databases. Selection criteria: Papers reporting cases of women infected with SARS-CoV-2 who delivered. Data collection and analysis: The following was extracted: author; country; number of women; study design; gestational age at delivery; selected clinical maternal data; mode of delivery; selected neonatal outcomes. Main results: In the 13 studies included, vaginal delivery was reported in 6 cases (9.4%; 95% CI, 3.5–19.3). Indication for cesarean delivery was worsening of maternal conditions in 31 cases (48.4%; 95% CI, 35.8–61.3). Two newborns testing positive for SARS-CoV-2 by real-time RT-PCR assay were reported. In three neonates, SARS-CoV-2 IgG and IgM levels were elevated but the RT-PCR test was negative. Conclusions: The rate of vertical or peripartum transmission of SARS-CoV-2 is low, if any, for cesarean delivery; no data are available for vaginal delivery. Low frequency of spontaneous preterm birth and general favorable immediate neonatal outcome are reassuring.
Delivery in pregnant women infected with SARS-CoV-2: A fast review / F. Parazzini, R. Bortolus, P.A. Mauri, A. Favilli, S. Gerli, E. Ferrazzi. - In: INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS. - ISSN 0020-7292. - 150:1(2020 Jul 01), pp. 41-46.
|Titolo:||Delivery in pregnant women infected with SARS-CoV-2: A fast review|
PARAZZINI, FABIO (Primo) (Corresponding)
FERRAZZI, ENRICO MARIO (Ultimo)
|Parole Chiave:||Cesarean delivery; COVID-19; Neonatal outcome; Pregnancy; Review; SARS-CoV-2; Vaginal delivery; Vertical transmission; Adult; Cesarean Section; Coronavirus Infections; Delivery, Obstetric; Female; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Pandemics; Pneumonia, Viral; Pregnancy; Pregnancy Complications, Infectious; Premature Birth; Betacoronavirus|
|Settore Scientifico Disciplinare:||Settore MED/40 - Ginecologia e Ostetricia|
Settore MED/47 - Scienze Infermieristiche Ostetrico-Ginecologiche
|Data di pubblicazione:||1-lug-2020|
|Data ahead of print / Data di stampa:||mag-2020|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1002/ijgo.13166|
|Appare nelle tipologie:||01 - Articolo su periodico|