Background: Few case reports and clinical series exist on pregnant women infected with SARS-CoV-2 who delivered. Objective: To review the available information on mode of delivery, vertical/peripartum transmission, and neonatal outcome in pregnant women infected with SARS-CoV-2. Search strategy: Combination of the following key words: COVID-19, SARS-CoV-2, and pregnancy in Embase and PubMed databases. Selection criteria: Papers reporting cases of women infected with SARS-CoV-2 who delivered. Data collection and analysis: The following was extracted: author; country; number of women; study design; gestational age at delivery; selected clinical maternal data; mode of delivery; selected neonatal outcomes. Main results: In the 13 studies included, vaginal delivery was reported in 6 cases (9.4%; 95% CI, 3.5–19.3). Indication for cesarean delivery was worsening of maternal conditions in 31 cases (48.4%; 95% CI, 35.8–61.3). Two newborns testing positive for SARS-CoV-2 by real-time RT-PCR assay were reported. In three neonates, SARS-CoV-2 IgG and IgM levels were elevated but the RT-PCR test was negative. Conclusions: The rate of vertical or peripartum transmission of SARS-CoV-2 is low, if any, for cesarean delivery; no data are available for vaginal delivery. Low frequency of spontaneous preterm birth and general favorable immediate neonatal outcome are reassuring.
Delivery in pregnant women infected with SARS-CoV-2: A fast review / F. Parazzini, R. Bortolus, P.A. Mauri, A. Favilli, S. Gerli, E. Ferrazzi. - In: INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS. - ISSN 0020-7292. - 150:1(2020 Jul 01), pp. 41-46.
Titolo: | Delivery in pregnant women infected with SARS-CoV-2: A fast review |
Autori: | FERRAZZI, ENRICO MARIO (Ultimo) |
Parole Chiave: | Cesarean delivery; COVID-19; Neonatal outcome; Pregnancy; Review; SARS-CoV-2; Vaginal delivery; Vertical transmission; Adult; Cesarean Section; Coronavirus Infections; Delivery, Obstetric; Female; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Pandemics; Pneumonia, Viral; Pregnancy; Pregnancy Complications, Infectious; Premature Birth; Betacoronavirus |
Settore Scientifico Disciplinare: | Settore MED/40 - Ginecologia e Ostetricia Settore MED/47 - Scienze Infermieristiche Ostetrico-Ginecologiche |
Data di pubblicazione: | 1-lug-2020 |
Rivista: | |
Tipologia: | Article (author) |
Data ahead of print / Data di stampa: | mag-2020 |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1002/ijgo.13166 |
Appare nelle tipologie: | 01 - Articolo su periodico |
File in questo prodotto:
File | Descrizione | Tipologia | Licenza | |
---|---|---|---|---|
IJG revised.pdf | Pre-print (manoscritto inviato all'editore) | Open Access Visualizza/Apri | ||
ijgo.13166.pdf | Publisher's version/PDF | Open Access Visualizza/Apri |