The first synthesis of 1-aminoglucose analogue of the antitumor agent etoposide is accomplished by condensation of 4,6-tO-ethylidene-2,3-di-tO-trimethylsilyl-β-D-glucopyranosylamine with 4-bromo-4-deoxy-4′-demethylepipodophyllotoxin in the presence of Hg(CN)2.
The first synthesis of the N-glucosyl analogue of the antitumor agent etoposide / P. Allevi, M. Anastasia, P. Ciuffreda. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 34:45(1993), pp. 7313-7316.
The first synthesis of the N-glucosyl analogue of the antitumor agent etoposide
P. Allevi
Primo
;M. AnastasiaSecondo
;P. CiuffredaUltimo
1993
Abstract
The first synthesis of 1-aminoglucose analogue of the antitumor agent etoposide is accomplished by condensation of 4,6-tO-ethylidene-2,3-di-tO-trimethylsilyl-β-D-glucopyranosylamine with 4-bromo-4-deoxy-4′-demethylepipodophyllotoxin in the presence of Hg(CN)2.File in questo prodotto:
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