Persistent trigeminal artery (PTA) originates from the posterior bend or lateral wall of the intra-cavernous carotid artery and is the most common occurring type of remnant primitive fetal arteries. In literature, there is limited number of reports on migraine-cephalgia (MC) associated with coexisting PTA. The primitive anastomose arteries that fully belong to the intracranial arterial vascular system are not supposed to perform any supportive functional activity; usually they are subjected to normal biological decay caused by the aging process and metabolic dysfunctions. The hypothesis suggests that these primitive fetal arteries such as PTA may not undergo a fast and structural deterioration but they might be active contributors to a series of mechanisms that can cause a variety of idiopathic complaints. Consequently this would bring a different therapeutic approach other than their surgical removal, which is the accepted option today as a solution for these problems. In this case report, a chronic unilateral MC due to coexisting PTA adjacent to trigeminal nerve is presented. The caliber and location of the PTA was confirmed by a CT-Angiography. The MC treatment was achieved by administration of bio-identical testosterone, human placenta extract (HPE), b-nicotinamide adenine dinucleotide (NADH) and low dose amlopidine.
Chronic migraine-cephalgia related to trigeminal artery: a case report of innovative regenerative approach / C. Gargiulo Isacco, F. Inchingolo, K.C.D. Nguyen, A. Ballini, M. Schiffman, S.K. Aityan, C. Mortellaro, K.Q. Hong, N.V. Vo, S. Cantore, G. Dipalma, T.C. Tran, F. Goker, M. Del Fabbro, A. Greco Lucchina. - In: JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS. - ISSN 0393-974X. - 33:6 Suppl. 2(2019 Nov 01), pp. 23-29.
|Titolo:||Chronic migraine-cephalgia related to trigeminal artery: a case report of innovative regenerative approach|
|Parole Chiave:||B-nicotinamide adenine dinucleotide; CT-angiography; estrogen; human placenta extract; migraine-cephalgia; persistent trigeminal artery; progesterone; testosterone; trigeminal nerve|
|Settore Scientifico Disciplinare:||Settore MED/28 - Malattie Odontostomatologiche|
Settore MED/50 - Scienze Tecniche Mediche Applicate
|Data di pubblicazione:||1-nov-2019|
|Appare nelle tipologie:||01 - Articolo su periodico|