OBJECTIVE: To report mode of delivery and immediate neonatal outcome in COVID-19 infected women. DESIGN: This is a retrospective study. SETTING: Twelve hospitals in northern Italy. PARTICIPANTS: Pregnant women with COVID-19 confirmed infection who delivered. EXPOSURE: COVID 19 infection in pregnancy. METHODS: SARS-CoV-2 infected women who were admitted and delivered during the period 1-20 march 2020 were eligible. Data were collected from the clinical records using a standardized questionnaire on maternal general characteristics, any medical or obstetric co-morbidity, course of pregnancy, clinical signs and symptoms, treatment of COVID 19 infection, mode of delivery, neonatal data and breastfeeding MAIN OUTCOME AND MEASURE: Data on mode of delivery and neonatal outcome RESULTS: 42 women with COVID-19 delivered at the participating centres: 24(57,1%, 95% CI= 41,0-72,3) delivered vaginally. An elective cesarean section was performed in 18/42 (42,9%, 95%CI 27,7-59,0) cases: in 8 cases the indication was unrelated to COVID-19 infection. Pneumonia was diagnosed in 19/42(45,2%, 95%CI 29,8-61,3) cases: of these 7/19(36,8%,95CI 16,3-61,6) required oxygen support and 4/19(21,1%,95%CI=6,1-45,6) were admitted to a critical care unit. Two women with COVID-19 breastfed without a mask because infection was diagnosed in the post-partum period: their new-borns tested positive for SARS-Cov-2 infection. In one case a new-born had a positive test after a vaginal operative delivery. CONCLUSIONS: Although post-partum infection cannot be excluded with 100% certainty, these findings suggest that vaginal delivery is associated with a low risk of intrapartum SARS-Cov-2 transmission to the new-born.
Vaginal delivery in SARS-CoV-2 infected pregnant women in Northern Italy: a retrospective analysis / E. Ferrazzi, L. Frigerio, V. Savasi, P. Vergani, F. Prefumo, S. Barresi, S. Bianchi, E. Ciriello, F. Facchinetti, M.T. Gervasi, E. Iurlaro, A. Kustermann, G. Mangili, F. Mosca, L. Patanè, D. Spazzini, A. Spinillo, G. Trojano, M. Vignali, A. Villa, G. Zuccotti, F. Parazzini, I. Cetin. - In: BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY. - ISSN 1470-0328. - 127:9(2020 Aug), pp. 1116-1121.
|Titolo:||Vaginal delivery in SARS-CoV-2 infected pregnant women in Northern Italy: a retrospective analysis|
FERRAZZI, ENRICO MARIO (Primo)
PARAZZINI, FABIO (Penultimo) (Corresponding)
CETIN, IRENE (Ultimo)
|Parole Chiave:||COVID-19; delivery; transmission;|
|Settore Scientifico Disciplinare:||Settore MED/40 - Ginecologia e Ostetricia|
|Data di pubblicazione:||ago-2020|
|Data ahead of print / Data di stampa:||27-apr-2020|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1111/1471-0528.16278|
|Appare nelle tipologie:||01 - Articolo su periodico|