To assess mid-term outcome of biodegradable biliary stents (BBSs) to treat benign biliary strictures refractory to standard bilioplasty. Institutional review board approval was obtained and patient consent was waived. 107 patients (61 males, 46 females, mean age 59 +/- 16 years), were treated. Technical success and complications were recorded. Ninety-seven patients (55 males, 42 females, aged 57 +/- 17 years) were considered for follow-up analysis (mean follow-up 23 +/- 12 months). Fisher's exact test and Mann-Whitney U tests were used and a Kaplan-Meier curve was calculated. The procedure was always feasible. In 2/107 cases (2 %), stent migration occurred (technical success 98 %). 4/107 patients (4 %) experienced mild haemobilia. No major complications occurred. In 19/97 patients (18 %), stricture recurrence occurred. In this group, higher rate of subsequent cholangitis (84.2 % vs. 12.8 %, p = 0.001) and biliary stones (26.3 % vs. 2.5 %, p = 0.003) was noted. Estimated mean time to stricture recurrence was 38 months (95 % C.I 34-42 months). Estimated stricture recurrence rate at 1, 2, and 3 years was respectively 7.2 %, 26.4 %, and 29.4 %. Percutaneous placement of a BBS is a feasible and safe strategy to treat benign biliary strictures refractory to standard bilioplasty, with promising results in the mid-term period. aEuro cent Percutaneous placement of a BBS is 100 % feasible. aEuro cent The procedure appears free from major complications, with few minor complications. aEuro cent BBSs offer promising results in the mid-term period. aEuro cent With a BBS, external catheter/drainage can be removed early. aEuro cent BBSs represent a new option in treating benign biliary stenosis.
Benign biliary strictures refractory to standard bilioplasty treated using polydoxanone biodegradable biliary stents: retrospective multicentric data analysis on 107 patients / G. Mauri, C. Michelozzi, F. Melchiorre, D. Poretti, V. Pedicini, M. Salvetti, E. Criado, J. Falco Fages, M.A. De Gregorio, A. Laborda, L.M. Sonfienza, G. Cornalba, L. Monfardini, J. Panek, T. Andrasina, M. Gimenez. - In: EUROPEAN RADIOLOGY. - ISSN 0938-7994. - 26:11(2016), pp. 4057-4063.
|Titolo:||Benign biliary strictures refractory to standard bilioplasty treated using polydoxanone biodegradable biliary stents: retrospective multicentric data analysis on 107 patients|
|Parole Chiave:||Biliary stricture; Percutaneous transhepatic cholangiography; Percutaneous transhepatic bilioplasty; Bioabsorbable biliary stent|
|Settore Scientifico Disciplinare:||Settore MED/36 - Diagnostica per Immagini e Radioterapia|
|Data di pubblicazione:||2016|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1007/s00330-016-4278-6|
|Appare nelle tipologie:||01 - Articolo su periodico|
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