The Author traces the evolution of fat grafting over the years from the first publication in 1893, to the systematization of the technique thanks to the contribution of Sydney Coleman. In recent years studies on the nature of adipose tissue have shown that besides multiple resident cells, fat tissue contains stem cells (ADSCs) capable of differentiating in multiple lineages, such as bone, cartilage, muscle, nerve, etc. Thus, in addition to the traditional notion that fat is a high energy reservoir, it becomes apparent that fat is a repair organ providing the basis for soft tissue regeneration. Manipulation of ADSCs promises to affect different fields of medicine and provide the physician with a variety of regenerative medical therapies.

The evolution of fat grafting : from soft tissue augmentation to regenerative medicine / R.F. Mazzola - In: Fat injection : from filling to regeneration / [a cura di] S.R. Coleman, R.F. Mazzola. - St. Louis : Quality medical publishing, 2009. - ISBN 9781576262849. - pp. XIX-XXXVIII

The evolution of fat grafting : from soft tissue augmentation to regenerative medicine

R.F. Mazzola
Primo
2009

Abstract

The Author traces the evolution of fat grafting over the years from the first publication in 1893, to the systematization of the technique thanks to the contribution of Sydney Coleman. In recent years studies on the nature of adipose tissue have shown that besides multiple resident cells, fat tissue contains stem cells (ADSCs) capable of differentiating in multiple lineages, such as bone, cartilage, muscle, nerve, etc. Thus, in addition to the traditional notion that fat is a high energy reservoir, it becomes apparent that fat is a repair organ providing the basis for soft tissue regeneration. Manipulation of ADSCs promises to affect different fields of medicine and provide the physician with a variety of regenerative medical therapies.
History of Medicine ; Fat grafting ; Stem cells
Settore MED/31 - Otorinolaringoiatria
2009
Book Part (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/73053
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