Aim: to discuss the rationale of the management of penile MALT lymphoma. Case Report: A 24-year-old patient presented with a painless and mobile nodule localized in the ventral part of the penis. The lesion was firstly evaluated through Doppler ultrasonography, which showed a hypoechoic and vascularized solid mass, a subsequent magnetic resonance confirmed size and position of the lesion. Subsequetly the patient underwent a surgical excision of the mass, the pathological diagnosis was consistent with penile lymphoma, MALT-type. The patient underwent a consolidative immunotherapy with rituximab. Disease re-staging was performed through a MR without any detection of local or systemic recurrences. Conclusion: To our knowledge, no cases of MALT lymphoma involving the penis have been reported in the literature so far. Surgical excision with organ sparing and immunotherapy with rituximab, successfully induced a complete response. Based upon this experience, we may recommend a conservative surgery associated with a systemic approach.

An isolated penile mass in a young adult turned out to be a primary marginal zone lymphoma of the penis : a case report and a review of literature / G. Gentile, A. Broccoli, E. Brunocilla, R. Schiavina, M. Borghesi, D. Romagnoli, L. Bianchi, E. Derenzini, C. Agostinelli, A. Franceschelli, F. Colombo, P.L. Zinzani. - In: ANTICANCER RESEARCH. - ISSN 0250-7005. - 33:6(2013), pp. 2639-2642.

An isolated penile mass in a young adult turned out to be a primary marginal zone lymphoma of the penis : a case report and a review of literature

E. Derenzini;
2013

Abstract

Aim: to discuss the rationale of the management of penile MALT lymphoma. Case Report: A 24-year-old patient presented with a painless and mobile nodule localized in the ventral part of the penis. The lesion was firstly evaluated through Doppler ultrasonography, which showed a hypoechoic and vascularized solid mass, a subsequent magnetic resonance confirmed size and position of the lesion. Subsequetly the patient underwent a surgical excision of the mass, the pathological diagnosis was consistent with penile lymphoma, MALT-type. The patient underwent a consolidative immunotherapy with rituximab. Disease re-staging was performed through a MR without any detection of local or systemic recurrences. Conclusion: To our knowledge, no cases of MALT lymphoma involving the penis have been reported in the literature so far. Surgical excision with organ sparing and immunotherapy with rituximab, successfully induced a complete response. Based upon this experience, we may recommend a conservative surgery associated with a systemic approach.
MALT lymphoma; penile tumor
Settore MED/15 - Malattie del Sangue
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/724994
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