Mutations in the dystrophin gene cause an X-linked genetic disorder: Duchenne muscular dystrophy (DMD). Stem cell therapy is an attractive method to treat DMD because a small number of cells are required to obtain a therapeutic effect. Here, we discussed about multiple types of myogenic stem cells and their possible use to treat DMD. The identification of a stem cell population providing efficient muscle regeneration is critical for the progression of cell therapy for DMD. We speculated that the most promising possibility for the treatment of DMD is a combination of different approaches, such as gene and stem cell therapy.

Cell Based Therapy for Duchenne Muscular Dystrophy [Recensione] / A. Farini, P. Razini, S. Erratico, Y. Torrente, M. Meregalli. - In: JOURNAL OF CELLULAR PHYSIOLOGY. - ISSN 0021-9541. - 221:3(2009 Aug 17), pp. 526-534.

Cell Based Therapy for Duchenne Muscular Dystrophy

A. Farini;P. Razini;S. Erratico;Y. Torrente;M. Meregalli
2009-08-17

Abstract

Mutations in the dystrophin gene cause an X-linked genetic disorder: Duchenne muscular dystrophy (DMD). Stem cell therapy is an attractive method to treat DMD because a small number of cells are required to obtain a therapeutic effect. Here, we discussed about multiple types of myogenic stem cells and their possible use to treat DMD. The identification of a stem cell population providing efficient muscle regeneration is critical for the progression of cell therapy for DMD. We speculated that the most promising possibility for the treatment of DMD is a combination of different approaches, such as gene and stem cell therapy.
Settore MED/26 - Neurologia
JOURNAL OF CELLULAR PHYSIOLOGY
Article (author)
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/71641
Citazioni
  • ???jsp.display-item.citation.pmc??? 25
  • Scopus 55
  • ???jsp.display-item.citation.isi??? 47
social impact