A dynamic model has been developed to quantitate the dynamics of growth of Escherichia coli. The model integrates the preexisting models of chromosome replication and cell division by incorporating a description of the synthesis and degradation of ribosomes and protein. Relevant features of the model are: a threshold control for DNA synthesis and a double feedback mechanism that controls ribosome synthesis. The model generates accurate predictions of the kinetics of growth and cell composition of Escherichia coli B/r cells, each growth condition being defined by a set of parameters.
Modeling microbial growth: A model of growth and cell division of escherichia coli / L. Alberghina, E. Martegani, L. Popolo. - In: BOLLETTINO DI ZOOLOGIA. - ISSN 0373-4137. - 46:3(1979), pp. 127-135. [10.1080/11250007909440291]
Modeling microbial growth: A model of growth and cell division of escherichia coli
L. Popolo
1979
Abstract
A dynamic model has been developed to quantitate the dynamics of growth of Escherichia coli. The model integrates the preexisting models of chromosome replication and cell division by incorporating a description of the synthesis and degradation of ribosomes and protein. Relevant features of the model are: a threshold control for DNA synthesis and a double feedback mechanism that controls ribosome synthesis. The model generates accurate predictions of the kinetics of growth and cell composition of Escherichia coli B/r cells, each growth condition being defined by a set of parameters.File | Dimensione | Formato | |
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