PURPOSE: To analyze radiographic and histological outcomes of maxillary sinus floor augmentation using a calcium-sulfate based allograft containing demineralized bone matrix particles. MATERIALS AND METHODS: Fifteen maxillary sinus lift procedures with simultaneous placement of titanium implants were performed in 12 patients of both genders aged 36-71 years. Each sinus cavity was filled by the biocomposite. After 3 months of healing, all surgical sites were uncovered and bone biopsies were retrieved for undecalcified histology and histomorphometry. The ratio between the original and the grafted sinus height (GSH/OSH) was computed using a panoramic radiography taken immediately after surgery and at 3 months of healing, and the two ratios were compared by Wilcoxon signed-rank test. RESULTS: By 3 months, all implants were stable without clinical and radiographic signs of infection. Significant changes in GSH/OSH during healing were seen (2.7 +/- 0.6 initially vs. 2.6 +/- 0.5 after healing; p = 0.01). Histologic findings showed newly formed bone surrounding the residual grafted particles without inflammation. At 3 months, mean regenerated bone density was 33.8 +/- 8.6%; marrow spaces amounted to 32.3 +/- 10.3%; residual graft was 33.9 +/- 9.0%. Similar histomorphometric and radiographic results were obtained independently from patient age or sex. CONCLUSIONS: The analysed putty seems to be a safe and effective graft material for maxillary sinus floor augmentation by accelerating bone regeneration and thus reducing the healing time.

Histomorphometric analysis of human maxillary sinus lift with a new bone substitute biocomposite : a preliminary report / C. Dellavia, G.M. Tartaglia, C. Sforza. - In: CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH. - ISSN 1523-0899. - 11:suppl. 1(2009), pp. e59-e68. [10.1111/j.1708-8208.2009.00203.x]

Histomorphometric analysis of human maxillary sinus lift with a new bone substitute biocomposite : a preliminary report

C. Dellavia
Primo
;
G.M. Tartaglia
Secondo
;
C. Sforza
Ultimo
2009

Abstract

PURPOSE: To analyze radiographic and histological outcomes of maxillary sinus floor augmentation using a calcium-sulfate based allograft containing demineralized bone matrix particles. MATERIALS AND METHODS: Fifteen maxillary sinus lift procedures with simultaneous placement of titanium implants were performed in 12 patients of both genders aged 36-71 years. Each sinus cavity was filled by the biocomposite. After 3 months of healing, all surgical sites were uncovered and bone biopsies were retrieved for undecalcified histology and histomorphometry. The ratio between the original and the grafted sinus height (GSH/OSH) was computed using a panoramic radiography taken immediately after surgery and at 3 months of healing, and the two ratios were compared by Wilcoxon signed-rank test. RESULTS: By 3 months, all implants were stable without clinical and radiographic signs of infection. Significant changes in GSH/OSH during healing were seen (2.7 +/- 0.6 initially vs. 2.6 +/- 0.5 after healing; p = 0.01). Histologic findings showed newly formed bone surrounding the residual grafted particles without inflammation. At 3 months, mean regenerated bone density was 33.8 +/- 8.6%; marrow spaces amounted to 32.3 +/- 10.3%; residual graft was 33.9 +/- 9.0%. Similar histomorphometric and radiographic results were obtained independently from patient age or sex. CONCLUSIONS: The analysed putty seems to be a safe and effective graft material for maxillary sinus floor augmentation by accelerating bone regeneration and thus reducing the healing time.
Allograft; Histology; Maxillary sinus floor augmentation
Settore BIO/16 - Anatomia Umana
2009
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/71371
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