Risk Factors for SAMS

The identification of patient characteristics associated with SAMS may help to better understand and predict this unwanted effect of statins. The clinical data reported for patients with SAMS allows the identification of predisposing factors that can be divided into both endogenous (demographics, medical history) and exogenous (diet or life-style and concurrent medications) factors. Attention to the potential for muscle problems with statin therapy, in particular when they are given in combination with other drugs, in the presence of particular life-style conditions or dietary components should help reducing the risk of muscle events.