Stage classification is an important underpinning of management of patients with cancer, and rests on a combination of three components: T for tumor extent, N for nodal involvement, and M for more distant metastases. This article details an initiative to develop proposals for the first official stage classification system for thymic malignancies for the 8th edition of the stage classification manuals. Specifically, the results of analysis of a large database and the considerations leading to the proposed N and M components are described. Nodal involvement is divided into an anterior (N1) and a deep (N2) category. Metastases can involve pleural or pericardial nodules (M1a) or intraparenchymal pulmonary nodules or metastases to distant sites (M1b).

The IASLC/ITMIG thymic epithelial tumors staging project: Proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors / K. Kondo, P. Van Schil, F.C. Detterbeck, M. Okumura, D. Giroux, H. Asamura, J. Crowley, C. Falkson, P.L. Filosso, G. Giaccone, J. Huang, J. Kim, M. Lucchi, M. Marino, E.M. Marom, A.G. Nicholson, E. Ruffini, P. Goldstraw, R. Rami-Porta, D. Ball, D. Beer, R. Beyruti, V. Bolejack, K. Chansky, W.E.E. Eberhardt, J. Edwards, F. Galateau-Salle, F. Gleeson, P. Groome, C. Kennedy, L. Kingsbury, Y.T. Kim, H. Kondo, M. Krasnik, K. Kubota, A. Lerut, G. Lyons, J. Van Meerbeeck, A. Mitchell, T. Nakano, A. Nowak, M. Peake, T. Rice, K. Rosenzweig, V. Rusch, N. Saijo, J.-. Sculier, L. Shemanski, K. Stratton, K. Suzuki, Y. Tachimori, C.F. Thomas, W. Travis, M.S. Tsao, A. Turrisi, J. Vansteenkiste, H. Watanabe, Y.-. Wu, P. Baas, J. Erasmus, S. Hasegawa, K. Inai, K. Kernstine, H. Kindler, L. Krug, K. Nackaerts, H. Pass, D. Rice, E. Blackstone, S. Call Caja, U. Ahmad, F. Detterbeck, N. Girard, S.J. Haam, D.R. Gomez, M.K. Bae, P. Strobel, A. Marx, S. Saita, H. Wakelee, L. Bertolaccini, E. Vallieres, W. Scott, S. Su, B. Park, J. Marks, S. Khella, R. Shen, M. Rosenberg, V. Tomulescu, C. Foroulis, L. Lang-Lazdunski, A. Bille, J.G. Maessen, M. Keijzers, H. Van Veer, C. Wright, F. Facciolo, G. Palmieri, C. Buonerba, M. Ferguson, G. Marulli, P. Loehrer, M. Kalkat, K. Rohrberg, G. Daugaard, A. Toker, S. Erus, M. Kimmich, A. Brunelli, M. Refai, A. Nicholson, E. Lim, I.K. Park, J. Wagner, B. Tieu, W. Fang, J. Zhang, Z. Yu, Y. Han, Y. Li, K. Chen, G. Chen, K. Nagai, Y. Fujii, J. Nakajima, N. Ikeda, S. Haraguchi, T. Onuki, I. Yoshino, M. Tsuchida, S. Takahashi, K. Yokoi, M. Hanyuda, H. Niwa, H. Date, Y. Maniwa, S. Miyoshi, A. Iwasaki, T. Okamoto, T. Nagayasu, F. Tanaka, M. Suzuki, K. Yoshida, Y. Okuma, H. Horio, A. Matsumura, M. Higashiyama, H. Suehisa, T. Onuki, Y. Sano, K. Kondo, K. Al Kattan, R. Cerfolio, C. Gebitekin, D. Gomez De Antonio, K.H. Kernstine, N. Altorki, N. Novoa, M. Scarci, L. Voltolini, W. Weder, W. Zurek, A. Arame, C. Casadio, P. Carbognani, G. Donati, S. Keshavjee, W. Klepetko, B. Moser, C. Lequaglie, M. Liberman, M. Mancuso, M. Nosotti, L. Spaggiari, P.A. Thomas, E. Rendina, F. Venuta, M. Anile, J. Schutzner, G. Rocco. - In: JOURNAL OF THORACIC ONCOLOGY. - ISSN 1556-0864. - 9:9(2014), pp. S81-S87.

The IASLC/ITMIG thymic epithelial tumors staging project: Proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors

M. Nosotti;L. Spaggiari;
2014

Abstract

Stage classification is an important underpinning of management of patients with cancer, and rests on a combination of three components: T for tumor extent, N for nodal involvement, and M for more distant metastases. This article details an initiative to develop proposals for the first official stage classification system for thymic malignancies for the 8th edition of the stage classification manuals. Specifically, the results of analysis of a large database and the considerations leading to the proposed N and M components are described. Nodal involvement is divided into an anterior (N1) and a deep (N2) category. Metastases can involve pleural or pericardial nodules (M1a) or intraparenchymal pulmonary nodules or metastases to distant sites (M1b).
English
Staging; Prognosis; Thymoma; Thymic carcinoma; Stage classification
Settore MED/21 - Chirurgia Toracica
Articolo
Esperti anonimi
Pubblicazione scientifica
2014
Elsevier Inc
9
9
S81
S87
7
Pubblicato
Periodico con rilevanza internazionale
Aderisco
info:eu-repo/semantics/article
The IASLC/ITMIG thymic epithelial tumors staging project: Proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors / K. Kondo, P. Van Schil, F.C. Detterbeck, M. Okumura, D. Giroux, H. Asamura, J. Crowley, C. Falkson, P.L. Filosso, G. Giaccone, J. Huang, J. Kim, M. Lucchi, M. Marino, E.M. Marom, A.G. Nicholson, E. Ruffini, P. Goldstraw, R. Rami-Porta, D. Ball, D. Beer, R. Beyruti, V. Bolejack, K. Chansky, W.E.E. Eberhardt, J. Edwards, F. Galateau-Salle, F. Gleeson, P. Groome, C. Kennedy, L. Kingsbury, Y.T. Kim, H. Kondo, M. Krasnik, K. Kubota, A. Lerut, G. Lyons, J. Van Meerbeeck, A. Mitchell, T. Nakano, A. Nowak, M. Peake, T. Rice, K. Rosenzweig, V. Rusch, N. Saijo, J.-. Sculier, L. Shemanski, K. Stratton, K. Suzuki, Y. Tachimori, C.F. Thomas, W. Travis, M.S. Tsao, A. Turrisi, J. Vansteenkiste, H. Watanabe, Y.-. Wu, P. Baas, J. Erasmus, S. Hasegawa, K. Inai, K. Kernstine, H. Kindler, L. Krug, K. Nackaerts, H. Pass, D. Rice, E. Blackstone, S. Call Caja, U. Ahmad, F. Detterbeck, N. Girard, S.J. Haam, D.R. Gomez, M.K. Bae, P. Strobel, A. Marx, S. Saita, H. Wakelee, L. Bertolaccini, E. Vallieres, W. Scott, S. Su, B. Park, J. Marks, S. Khella, R. Shen, M. Rosenberg, V. Tomulescu, C. Foroulis, L. Lang-Lazdunski, A. Bille, J.G. Maessen, M. Keijzers, H. Van Veer, C. Wright, F. Facciolo, G. Palmieri, C. Buonerba, M. Ferguson, G. Marulli, P. Loehrer, M. Kalkat, K. Rohrberg, G. Daugaard, A. Toker, S. Erus, M. Kimmich, A. Brunelli, M. Refai, A. Nicholson, E. Lim, I.K. Park, J. Wagner, B. Tieu, W. Fang, J. Zhang, Z. Yu, Y. Han, Y. Li, K. Chen, G. Chen, K. Nagai, Y. Fujii, J. Nakajima, N. Ikeda, S. Haraguchi, T. Onuki, I. Yoshino, M. Tsuchida, S. Takahashi, K. Yokoi, M. Hanyuda, H. Niwa, H. Date, Y. Maniwa, S. Miyoshi, A. Iwasaki, T. Okamoto, T. Nagayasu, F. Tanaka, M. Suzuki, K. Yoshida, Y. Okuma, H. Horio, A. Matsumura, M. Higashiyama, H. Suehisa, T. Onuki, Y. Sano, K. Kondo, K. Al Kattan, R. Cerfolio, C. Gebitekin, D. Gomez De Antonio, K.H. Kernstine, N. Altorki, N. Novoa, M. Scarci, L. Voltolini, W. Weder, W. Zurek, A. Arame, C. Casadio, P. Carbognani, G. Donati, S. Keshavjee, W. Klepetko, B. Moser, C. Lequaglie, M. Liberman, M. Mancuso, M. Nosotti, L. Spaggiari, P.A. Thomas, E. Rendina, F. Venuta, M. Anile, J. Schutzner, G. Rocco. - In: JOURNAL OF THORACIC ONCOLOGY. - ISSN 1556-0864. - 9:9(2014), pp. S81-S87.
reserved
Prodotti della ricerca::01 - Articolo su periodico
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Article (author)
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K. Kondo, P. Van Schil, F.C. Detterbeck, M. Okumura, D. Giroux, H. Asamura, J. Crowley, C. Falkson, P.L. Filosso, G. Giaccone, J. Huang, J. Kim, M. Lucchi, M. Marino, E.M. Marom, A.G. Nicholson, E. Ruffini, P. Goldstraw, R. Rami-Porta, D. Ball, D. Beer, R. Beyruti, V. Bolejack, K. Chansky, W.E.E. Eberhardt, J. Edwards, F. Galateau-Salle, F. Gleeson, P. Groome, C. Kennedy, L. Kingsbury, Y.T. Kim, H. Kondo, M. Krasnik, K. Kubota, A. Lerut, G. Lyons, J. Van Meerbeeck, A. Mitchell, T. Nakano, A. Nowak, M. Peake, T. Rice, K. Rosenzweig, V. Rusch, N. Saijo, J.-. Sculier, L. Shemanski, K. Stratton, K. Suzuki, Y. Tachimori, C.F. Thomas, W. Travis, M.S. Tsao, A. Turrisi, J. Vansteenkiste, H. Watanabe, Y.-. Wu, P. Baas, J. Erasmus, S. Hasegawa, K. Inai, K. Kernstine, H. Kindler, L. Krug, K. Nackaerts, H. Pass, D. Rice, E. Blackstone, S. Call Caja, U. Ahmad, F. Detterbeck, N. Girard, S.J. Haam, D.R. Gomez, M.K. Bae, P. Strobel, A. Marx, S. Saita, H. Wakelee, L. Bertolaccini, E. Vallieres, W. Scott, S. Su, B. Park, J. Marks, S. Khella, R. Shen, M. Rosenberg, V. Tomulescu, C. Foroulis, L. Lang-Lazdunski, A. Bille, J.G. Maessen, M. Keijzers, H. Van Veer, C. Wright, F. Facciolo, G. Palmieri, C. Buonerba, M. Ferguson, G. Marulli, P. Loehrer, M. Kalkat, K. Rohrberg, G. Daugaard, A. Toker, S. Erus, M. Kimmich, A. Brunelli, M. Refai, A. Nicholson, E. Lim, I.K. Park, J. Wagner, B. Tieu, W. Fang, J. Zhang, Z. Yu, Y. Han, Y. Li, K. Chen, G. Chen, K. Nagai, Y. Fujii, J. Nakajima, N. Ikeda, S. Haraguchi, T. Onuki, I. Yoshino, M. Tsuchida, S. Takahashi, K. Yokoi, M. Hanyuda, H. Niwa, H. Date, Y. Maniwa, S. Miyoshi, A. Iwasaki, T. Okamoto, T. Nagayasu, F. Tanaka, M. Suzuki, K. Yoshida, Y. Okuma, H. Horio, A. Matsumura, M. Higashiyama, H. Suehisa, T. Onuki, Y. Sano, K. Kondo, K. Al Kattan, R. Cerfolio, C. Gebitekin, D. Gomez De Antonio, K.H. Kernstine, N. Altorki, N. Novoa, M. Scarci, L. Voltolini, W. Weder, W. Zurek, A. Arame, C. Casadio, P. Carbognani, G. Donati, S. Keshavjee, W. Klepetko, B. Moser, C. Lequaglie, M. Liberman, M. Mancuso, M. Nosotti, L. Spaggiari, P.A. Thomas, E. Rendina, F. Venuta, M. Anile, J. Schutzner, G. Rocco
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/707219
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