Cirrhosis is the end‐stage and the turning point in the natural history of liver disease, as is the major determinant of hepatic decompensation and cancer. Chronic viral hepatitis, alcohol abuse and dysmetabolism are the major causes of this condition. However, individuals respond differently to liver damage triggers, and inherited factors and family history have a large role in explaining this variability.
Uncovering the genetics of cirrhosis: New plots for the usual suspects / L. Valenti. - In: LIVER INTERNATIONAL. - ISSN 1478-3223. - 40:2(2020), pp. 281-282. [10.1111/liv.14333]
Uncovering the genetics of cirrhosis: New plots for the usual suspects
L. Valenti
Primo
2020
Abstract
Cirrhosis is the end‐stage and the turning point in the natural history of liver disease, as is the major determinant of hepatic decompensation and cancer. Chronic viral hepatitis, alcohol abuse and dysmetabolism are the major causes of this condition. However, individuals respond differently to liver damage triggers, and inherited factors and family history have a large role in explaining this variability.
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