Background: BioEnterics Intragastric Balloon (BIB®) is a non-invasive, temporary and relatively safe procedure shown to be effective in the short-term treatment of obesity. Nowadays, BIB® does not show convincing evidence of significant long-term weight loss, as compared with conventional management, and data regarding changes in metabolic and nutritional parameters are lacking. Methods: Forty obese patients [11 males, 29 females, age 36.65±10.6 yr, body mass index (BMI) 44.9±8.9 kg/m2] were evaluated before and 3 and 6 months after BIB® placement by assessment of anthropometric and biochemical parameters as well as nutritional habits. Results: Patients showed a significant reduction in weight (–13.2±6.5%), BMI (–13.2%), waist circumference (–6.5 cm), and percentage of fat mass (–19.5%), but not fat-free mass. A significant improvement in insulin sensitivity but not in lipid pattern was seen. After BIB® insertion, a significant reduction in caloric intake was paralleled by a redistribution of nutrients; in particular, increased lipid (12.8%) and decreased carbohydrate (–11.7%) percentage, but not absolute intake was observed. Conclusion: These data show that BIB® improves anthropometric parameters, with reduction of fat mass and preservation of fat-free mass, as well as insulin resistance, but not other metabolic features. The observed change in dietary habits, with a relative increase in lipid intake, once BIB® is removed, might favor body weight regain and impact negatively on body weight composition and the other traits of the metabolic syndrome.
|Titolo:||Metabolic parameters after BioEnterics Intragastric Balloon placement in obese patients|
SBURLATI, LAURA FEDERICA (Secondo)
BECK PECCOZ, PAOLO LUIGI MARIA (Penultimo)
|Parole Chiave:||BIB®; Cardiovascular risk; Fat mass; Fat-free mass; Insulin-resistance; Nutritional habits; Obesity; Weight loss|
|Settore Scientifico Disciplinare:||Settore MED/13 - Endocrinologia|
|Data di pubblicazione:||2009|
|Appare nelle tipologie:||01 - Articolo su periodico|