In recent decades, drugs used to treat malaria infection have been shown to be beneficial for many other diseases, including viral infections. In particular, they have received special attention due to the lack of effective antiviral drugs against new emerging viruses (i.e., HIV, dengue virus, chikungunya virus, Ebola virus, etc.) or against classic infections due to drug-resistant viral strains (i.e., human cytomegalovirus). Here, we reviewed the in vitro/in vivo and clinical studies conducted to evaluate the antiviral activities of four classes of antimalarial drugs: Artemisinin derivatives, aryl-aminoalcohols, aminoquinolines, and antimicrobial drugs.
The Use of Antimalarial Drugs against Viral Infection / S. D'Alessandro, D. Scaccabarozzi, L. Signorini, F. Perego, D.P. Ilboudo, P. Ferrante, S. Delbue. - In: MICROORGANISMS. - ISSN 2076-2607. - 8:1(2020 Jan 08), pp. 85.1-85.26. [10.3390/microorganisms8010085]
The Use of Antimalarial Drugs against Viral Infection
S. D'Alessandro;D. Scaccabarozzi;L. Signorini;F. Perego;P. Ferrante;S. Delbue
2020
Abstract
In recent decades, drugs used to treat malaria infection have been shown to be beneficial for many other diseases, including viral infections. In particular, they have received special attention due to the lack of effective antiviral drugs against new emerging viruses (i.e., HIV, dengue virus, chikungunya virus, Ebola virus, etc.) or against classic infections due to drug-resistant viral strains (i.e., human cytomegalovirus). Here, we reviewed the in vitro/in vivo and clinical studies conducted to evaluate the antiviral activities of four classes of antimalarial drugs: Artemisinin derivatives, aryl-aminoalcohols, aminoquinolines, and antimicrobial drugs.File | Dimensione | Formato | |
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