The effects of administration of aspirin plus dipyridamole (ASA + DIP) compared with those of aspirin alone (ASA) were studied in a population of patients with peripheral vascular disease of the lower limbs, using non-invasive instrumental tests and clinical parameters. Fifty-four patients aged 40-74 years, all male, were randomly allocated to two groups, to be followed for two years; the first group received dipyridamole 225 mg plug ASA 600 mg/day p.o., and the second ASA 600 mg/day p.o., in three divided doses. During the treatment the free interval at treadmill, ankle/arm arterial pressure index (API), and plethysmography were evaluated. It was possible to analyze only the results of the first six months of treatment because of the large number of drop-outs due to side effects of ASA. API and the oscillographic index did not alter significantly in the two groups, whereas the authors observed a significant increase of the free interval at treadmill and improved results at plethysmography in the ASA + DIP-treated group compared with the ASA-treated group.

Aspirin plus dipyridamole in the peripheral vascular disease / M. Catalano, G. Carzaniga, G. Fiore. - In: INTERNATIONAL ANGIOLOGY. - ISSN 0392-9590. - 4:4(1985), pp. 29-30.

Aspirin plus dipyridamole in the peripheral vascular disease

M. Catalano
Writing – Original Draft Preparation
;
G. Carzaniga;
1985

Abstract

The effects of administration of aspirin plus dipyridamole (ASA + DIP) compared with those of aspirin alone (ASA) were studied in a population of patients with peripheral vascular disease of the lower limbs, using non-invasive instrumental tests and clinical parameters. Fifty-four patients aged 40-74 years, all male, were randomly allocated to two groups, to be followed for two years; the first group received dipyridamole 225 mg plug ASA 600 mg/day p.o., and the second ASA 600 mg/day p.o., in three divided doses. During the treatment the free interval at treadmill, ankle/arm arterial pressure index (API), and plethysmography were evaluated. It was possible to analyze only the results of the first six months of treatment because of the large number of drop-outs due to side effects of ASA. API and the oscillographic index did not alter significantly in the two groups, whereas the authors observed a significant increase of the free interval at treadmill and improved results at plethysmography in the ASA + DIP-treated group compared with the ASA-treated group.
Settore MED/09 - Medicina Interna
Article (author)
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/704912
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? ND
social impact