Objective: to evaluate the effect of smoking habits on carotid artery intima media thickness (IMT) in gender specific models. Methods: 936 women and 869 men were recruited for the study. Among men there were 358 never-, 298 former- and 213 current-smokers; corresponding figures for women were 755, 79, 102, respectively. Among the 692 former/current smokers, 299 men and 136 women were light-smokers (packyear<30) and 212 men and 45 women were heavy-smokers (packyear≥30). Results: In never smokers gender was a determinant of carotid IMT (0.92±0.27 vs 0.95±0.26; p=0.029). The inclusion into the analysis of former/current smokers strongly reduced the between sexes differences in IMT (p=ns, after data adjustment for confounding variables). In men, IMT was higher in current-smokers, lower in former- and lowest in never-smokers (p=0.018). In women, although a similar trend was observed, the differences between current-, former- and never-smokers did not reach the statistical significance (p=0.26). Similar results were obtained when the population studied was stratified in never-, light- or heavy smokers. Conclusions: Smoking habits reduce the between sexes differences in IMT usually observed when only never-smokers are considered. Funding: Research described in this article was supported in part by Philip Morris USA Inc. and Philip Morris International.
Smoking habits as determinant of carotid IMT in gender specific models / B. Frigerio, S. Castelnuovo, G. De Giosa, M. Amato, E. Tremoli, C.R. Sirtori, D. Baldassarre. - In: ATHEROSCLEROSIS SUPPLEMENTS. - ISSN 1567-5688. - 7:3(2006), pp. 260-260. ((Intervento presentato al 14. convegno XIV International Symposium on Atherosclerosis tenutosi a Roma nel 2006 [10.1016/S1567-5688(06)81046-9].
Smoking habits as determinant of carotid IMT in gender specific models
B. FrigerioPrimo
;S. CastelnuovoSecondo
;G. De Giosa;E. Tremoli;C.R. SirtoriPenultimo
;D. BaldassarreUltimo
2006
Abstract
Objective: to evaluate the effect of smoking habits on carotid artery intima media thickness (IMT) in gender specific models. Methods: 936 women and 869 men were recruited for the study. Among men there were 358 never-, 298 former- and 213 current-smokers; corresponding figures for women were 755, 79, 102, respectively. Among the 692 former/current smokers, 299 men and 136 women were light-smokers (packyear<30) and 212 men and 45 women were heavy-smokers (packyear≥30). Results: In never smokers gender was a determinant of carotid IMT (0.92±0.27 vs 0.95±0.26; p=0.029). The inclusion into the analysis of former/current smokers strongly reduced the between sexes differences in IMT (p=ns, after data adjustment for confounding variables). In men, IMT was higher in current-smokers, lower in former- and lowest in never-smokers (p=0.018). In women, although a similar trend was observed, the differences between current-, former- and never-smokers did not reach the statistical significance (p=0.26). Similar results were obtained when the population studied was stratified in never-, light- or heavy smokers. Conclusions: Smoking habits reduce the between sexes differences in IMT usually observed when only never-smokers are considered. Funding: Research described in this article was supported in part by Philip Morris USA Inc. and Philip Morris International.File | Dimensione | Formato | |
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