The present invention provides a new type of lipid nanoparticles comprising amphiphilic lipids suitable for the incorporation of peptides and/or proteins, in order to provide their controlled release, once they have been administered. In particular, the main object of the invention is to provide a new type of lipid nanoparticles comprising a drug, a lipid matrix and a surfactant characterized in that said drug is a peptide or a protein and said lipid matrix has a monoglyceride content which is at least 70% w/w, the percentage being based on the weight of the lipid matrix.

Amphiphilic lipid nanoparticles for peptide and/or protein incorporation / M. Del Curto, D. Chicco, E. Esposito.

Amphiphilic lipid nanoparticles for peptide and/or protein incorporation

M. Del Curto;
2002-07-04

Abstract

The present invention provides a new type of lipid nanoparticles comprising amphiphilic lipids suitable for the incorporation of peptides and/or proteins, in order to provide their controlled release, once they have been administered. In particular, the main object of the invention is to provide a new type of lipid nanoparticles comprising a drug, a lipid matrix and a surfactant characterized in that said drug is a peptide or a protein and said lipid matrix has a monoglyceride content which is at least 70% w/w, the percentage being based on the weight of the lipid matrix.
ARES TRADING S A
WO2002/051390
PCT/EP01/14877
http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&at=12&locale=en_EP&FT=D&CC=PT&NR=1345597E&KC=E
Amphiphilic lipid nanoparticles for peptide and/or protein incorporation / M. Del Curto, D. Chicco, E. Esposito.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/69722
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