Aims To assess EuroSCORE performance in predicting in-hospital mortality in on-pump coronary artery bypass grafting (CABG) and off-pump coronary artery bypass grafting (OPCAB). Methods and results Additive and logistic EuroSCORE were computed for consecutive patients undergoing CABG (n = 3440, 75%) or OPCAB (n = 1140, 25%) at our hospital from 1999 to September 2007. The areas under the receiver operating characteristic (ROC) curves (AUCs) were used to describe performance and accuracy. No difference in performance between CABG and OPCAB and between additive and logistic EuroSCORE (additive EuroSCORE AUCs of 0.808 and 0.779 for CABG and OPCAB, respectively; logistic EuroSCORE AUCs of 0.813 and of 0.773 for CABG and OPCAB, respectively) was found, although a marked tendency to overpredict mortality by both models was evident. A meta-analysis of previously published data was done, and a total of eight studies representing 19 212 and 5461 patients undergoing CABG and OPCAB, respectively, met inclusion criteria. Meta-analysis confirmed similar performance of EuroSCORE in CABG and OPCAB: estimated AUCs were 0.767 and 0.766 for CABG and OPCAB, respectively, with an estimated difference of 0.001 (95% CI 20.061 to 0.063). Conclusion Additive and logistic EuroSCORE algorithms performed similarly, and cumulative evidence suggests comparable performance in CABG and OPCAB procedures; both risk models, however, significantly overestimated mortality

Performance of EuroSCORE in CABG and off-pump coronary artery bypass grafting : single institution experience and meta-analysis / A. Parolari, L.L. Pesce, M. Trezzi, C.M. Loardi, S. Kassem, C. Brambillasca, B. Miguel, E. Tremoli, P. Biglioli, F. Alamanni. - In: EUROPEAN HEART JOURNAL. - ISSN 0195-668X. - 30:3(2009), pp. 297-304. [10.1093/eurheartj/ehn581]

Performance of EuroSCORE in CABG and off-pump coronary artery bypass grafting : single institution experience and meta-analysis

A. Parolari
Primo
;
M. Trezzi;C.M. Loardi;S. Kassem;E. Tremoli;P. Biglioli
Penultimo
;
F. Alamanni
Ultimo
2009

Abstract

Aims To assess EuroSCORE performance in predicting in-hospital mortality in on-pump coronary artery bypass grafting (CABG) and off-pump coronary artery bypass grafting (OPCAB). Methods and results Additive and logistic EuroSCORE were computed for consecutive patients undergoing CABG (n = 3440, 75%) or OPCAB (n = 1140, 25%) at our hospital from 1999 to September 2007. The areas under the receiver operating characteristic (ROC) curves (AUCs) were used to describe performance and accuracy. No difference in performance between CABG and OPCAB and between additive and logistic EuroSCORE (additive EuroSCORE AUCs of 0.808 and 0.779 for CABG and OPCAB, respectively; logistic EuroSCORE AUCs of 0.813 and of 0.773 for CABG and OPCAB, respectively) was found, although a marked tendency to overpredict mortality by both models was evident. A meta-analysis of previously published data was done, and a total of eight studies representing 19 212 and 5461 patients undergoing CABG and OPCAB, respectively, met inclusion criteria. Meta-analysis confirmed similar performance of EuroSCORE in CABG and OPCAB: estimated AUCs were 0.767 and 0.766 for CABG and OPCAB, respectively, with an estimated difference of 0.001 (95% CI 20.061 to 0.063). Conclusion Additive and logistic EuroSCORE algorithms performed similarly, and cumulative evidence suggests comparable performance in CABG and OPCAB procedures; both risk models, however, significantly overestimated mortality
EuroSCORE ; CABG ; OPCAB ; ROC analysis ; Meta-analysis
Settore MED/23 - Chirurgia Cardiaca
Settore BIO/14 - Farmacologia
Article (author)
File in questo prodotto:
File Dimensione Formato  
2009 EHJ ROCs.pdf

accesso solo dalla rete interna

Tipologia: Publisher's version/PDF
Dimensione 260.33 kB
Formato Adobe PDF
260.33 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/69686
Citazioni
  • ???jsp.display-item.citation.pmc??? 9
  • Scopus 60
  • ???jsp.display-item.citation.isi??? 57
social impact