In-stent restenosis (ISR) occurs in 20% to 40% of de novo coronary lesions treated with bare-metal stents (BMS), depending on lesion and patient-related factors. Drug-eluting stents coated with antiproliferative agents, represent a valid rationale for treatment and prevention of recurrent ISR, with low MACE rates. However, case reports and observational studies reported a definite increase in the incidence of late stent thrombosis after drug-eluting stents use, particularly in off-label cases and after clopidogrel withdrawal. The case we present shows target vessel occlusion occurring at the site of a previously implanted BMS, suggesting that in-stent restenosis was the main pathological mechanism leading to abrupt thrombotic vessel closure and acute myocardial infarction.
|Titolo:||Late occlusive in-stent restenosis of a bare-metal stent presenting with ST-elevation anterior MI : is restenosis better than a late stent thrombosis?|
|Parole Chiave:||Acute myocardial infarction; Bare-metal stents; Drug-eluting stents; Late stent thrombosis; Restenosis|
|Settore Scientifico Disciplinare:||Settore MED/11 - Malattie dell'Apparato Cardiovascolare|
|Data di pubblicazione:||26-giu-2009|
|Digital Object Identifier (DOI):||10.1016/j.ijcard.2008.04.027|
|Appare nelle tipologie:||01 - Articolo su periodico|